Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | BCR | P11274 | 2/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314785 | 1.00 | NPC1 (0.36) | NPC1MEN1KMT2AMAPTPOLB | |
| SCHEMBL315052 | 0.91 | — | — | |
| SCHEMBL3398537 | 0.91 | — | — | |
| SCHEMBL315009 | 0.89 | CASP1 (0.32) | MAPTMKNK1MKNK2 | |
| SCHEMBL3400288 | 0.89 | CASP1 (0.32) | MAPTMKNK1MKNK2 | |
| SCHEMBL314854 | 0.84 | CYP2A6 (0.39) | NPC1MEN1KMT2AMAPTPOLB | |
| SCHEMBL314853 | 0.84 | CYP2A6 (0.39) | NPC1MEN1KMT2AMAPTPOLB | |
| SCHEMBL316661 | 0.84 | MKNK1 (0.36) | MAPTALDH1A1MKNK1MKNK2CYP11B1 | |
| SCHEMBL2410997 | 0.84 | CHRNB4 (0.42) | POLBALDH1A1MKNK1MKNK2CYP11B1 | |
| SCHEMBL2411000 | 0.84 | CHRNB4 (0.42) | POLBALDH1A1MKNK1MKNK2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |