Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 3/20 | 0.32 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.32 |
| ▸ | CIT | O14578 | 1/20 | 0.30 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.30 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.30 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.30 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MYLK2 | Q9H1R3 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.30 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.30 |
| ▸ | TLK1 | Q9UKI8 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315009 | 1.00 | CASP1 (0.32) | CASP1MAP2K3CITDAPK3JAK2 | |
| SCHEMBL315052 | 0.90 | — | — | |
| SCHEMBL3398537 | 0.90 | — | — | |
| SCHEMBL314785 | 0.89 | NPC1 (0.36) | MKNK1MKNK2MAPT | |
| SCHEMBL3395672 | 0.89 | NPC1 (0.36) | MKNK1MKNK2MAPT | |
| SCHEMBL316307 | 0.89 | MAP2K3 (0.32) | MAP2K3DYRK1A | |
| SCHEMBL3399091 | 0.89 | MAP2K3 (0.32) | MAP2K3DYRK1A | |
| SCHEMBL313987 | 0.87 | AAK1 (0.35) | CITDAPK3JAK2DAPK1MAP2K1 | |
| SCHEMBL313988 | 0.87 | AAK1 (0.35) | CITDAPK3JAK2DAPK1MAP2K1 | |
| SCHEMBL314261 | 0.85 | NTMT1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |