SCHEMBL3395674

SCHEMBL3395674

C=C([SiH3])C(C)(C)CCCCC

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FDPS P14324 11/20 0.35
GGPS1 O95749 7/20 0.35
SMPD1 P17405 2/20 0.33
CES2 O00748 1/20 0.33
LPAR1 Q92633 1/20 0.33
LPAR3 Q9UBY5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3396650 0.82
SCHEMBL3072520 0.78 FDPS (0.37) FDPSGGPS1SMPD1CES2LPAR1
SCHEMBL28581939 0.78 GGPS1 (0.41) FDPSGGPS1SMPD1CES2LPAR1
SCHEMBL22040406 0.76 GGPS1 (0.40) FDPSGGPS1SMPD1CES2LPAR1
SCHEMBL18456753 0.73 FDPS (0.45) FDPSGGPS1SMPD1
SCHEMBL4957018 0.73 FDPS (0.33) FDPSGGPS1SMPD1CES2LPAR1
SCHEMBL2108808 0.72 FDPS (0.39) FDPSGGPS1SMPD1CES2LPAR1
SCHEMBL4863854 0.71 FDPS (0.35) FDPSGGPS1SMPD1CES2LPAR1
SCHEMBL4863856 0.71 FDPS (0.35) FDPSGGPS1SMPD1CES2LPAR1
SCHEMBL14743308 0.71 FDPS (0.36) FDPSGGPS1SMPD1CES2LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8314051-B2 Method of preparing 1-methylcyclopropene and applying the same to plants ERUM BIOTECHNOLOGIES INC. (KR) 2012-11-20 US disclosed
US-20100076242-A1 METHOD OF PREPARING 1-METHYLCYCLOPROPENE AND APPLYING THE SAME TO PLANTS JANSSEN PHARMACEUTICA NV (BE) 2010-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100076242-A1 METHOD OF PREPARING 1-METHYLCYCLOPROPENE AND APPLYING THE SAME TO PLANTS CHRM1, EMC1, CHRM2 FDPS 199/4885GGPS1 240/4885SMPD1 438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.