SCHEMBL3395904

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22703778	0.82	NCF1 (0.46)	NCF1ACHECACNA2D1CACNA1BCACNB1
	SCHEMBL22564969	0.78	NCF1 (0.43)	NCF1ACHECACNA2D1CACNA1BCACNB1
	SCHEMBL2796612	0.78	GBA1 (0.49)	ACHECACNA2D1CACNA1BCACNB1SIGMAR1
	SCHEMBL8237680	0.77	GBA1 (0.46)	ACHESIGMAR1MEN1KMT2ACYP1A2
	SCHEMBL30616172	0.77	GBA1 (0.46)	ACHESIGMAR1MEN1KMT2ACYP1A2
	SCHEMBL23173902	0.77	NCF1 (0.54)	NCF1ACHECACNA2D1CACNA1BCACNB1
	SCHEMBL25571706	0.77	NCF1 (0.54)	NCF1ACHECACNA2D1CACNA1BCACNB1
	SCHEMBL22565080	0.76	NCF1 (0.45)	NCF1ACHECACNA2D1CACNA1BCACNB1
	SCHEMBL24319344	0.76	NCF1 (0.45)	NCF1ACHECACNA2D1CACNA1BCACNB1
	SCHEMBL24319799	0.76	NCF1 (0.45)	NCF1ACHECACNA2D1CACNA1BCACNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.