Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 6/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HEXA | P06865 | 1/20 | 0.35 |
| ▸ | HEXB | P07686 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13425393 | 0.78 | CYP11B2 (0.47) | ATRTLR8ADORA2AADORA1DHFR | |
| SCHEMBL3397291 | 0.77 | MAOB (0.47) | TLR8ADORA2AADORA1DHFR | |
| SCHEMBL28151082 | 0.75 | ADORA2A (0.52) | ATRTLR8ADORA2AADORA1CCNT1 | |
| SCHEMBL28507020 | 0.75 | CCNT1 (0.60) | ATRTLR8ADORA2ACCNT1CCNA2 | |
| SCHEMBL30507485 | 0.75 | CCNT1 (0.60) | ATRTLR8ADORA2ACCNT1CCNA2 | |
| SCHEMBL31018102 | 0.75 | MPL (0.50) | ATRADORA2AADORA1ALOX5APFEN1 | |
| SCHEMBL3395736 | 0.75 | ADORA2A (0.50) | ATRADORA2AADORA1 | |
| SCHEMBL2324805 | 0.75 | MPL (0.50) | ATRADORA2AADORA1ALOX5APFEN1 | |
| SCHEMBL3398219 | 0.75 | ADORA2A (0.54) | ATRADORA2AADORA1 | |
| SCHEMBL27685311 | 0.75 | SMN1; SMN2 (0.54) | ATRTLR8ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |