Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ATR | Q13535 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13425393 | 0.79 | CYP11B2 (0.47) | ADORA2AADORA1ATRIDO1LMNA | |
| SCHEMBL31018102 | 0.79 | MPL (0.50) | ADORA2AADORA1ATRIDO1ALDH1A1 | |
| SCHEMBL3395736 | 0.79 | ADORA2A (0.50) | ADORA2AADORA1HSD17B10ATRLMNA | |
| SCHEMBL2324805 | 0.79 | MPL (0.50) | ADORA2AADORA1ATRIDO1ALDH1A1 | |
| SCHEMBL27685311 | 0.79 | SMN1; SMN2 (0.54) | ADORA2AADORA1ATRIDO1LMNA | |
| SCHEMBL3431861 | 0.79 | HSP90AA1 (0.57) | ADORA2AADORA1HSD17B10ATRIDO1 | |
| SCHEMBL13425671 | 0.77 | ATR (0.46) | ADORA2AADORA1HSD17B10ATRLMNA | |
| SCHEMBL3395949 | 0.75 | ATR (0.48) | ADORA2AADORA1ATR | |
| SCHEMBL3128136 | 0.75 | ATR (0.48) | ADORA2AADORA1ATRPTPN1 | |
| SCHEMBL3393346 | 0.75 | HSP90AA1 (0.59) | ADORA2AADORA1HSD17B10ATRPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |