Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315594 | 1.00 | JAK2 (0.31) | JAK2 | |
| SCHEMBL3395477 | 0.88 | JAK2 (0.31) | JAK2 | |
| SCHEMBL315288 | 0.88 | JAK2 (0.31) | JAK2 | |
| SCHEMBL314156 | 0.86 | F2R (0.32) | — | |
| SCHEMBL314155 | 0.86 | F2R (0.32) | — | |
| SCHEMBL2407398 | 0.86 | KMO (0.34) | JAK2 | |
| SCHEMBL2407402 | 0.86 | KMO (0.34) | JAK2 | |
| SCHEMBL314645 | 0.84 | OPRK1 (0.32) | — | |
| SCHEMBL314644 | 0.84 | OPRK1 (0.32) | — | |
| SCHEMBL1973746 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2066683-B1 | DERIVATIVES OF 5-THIOXYLOPYRANOSE AND USE OF SAME FOR TREATMENT | FOURNIER LAB SA (FR) | 2010-11-03 | — | — | EP | disclosed |