Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.45 |
| ▸ | PPARA | Q07869 | 13/20 | 0.45 |
| ▸ | PPARD | Q03181 | 8/20 | 0.45 |
| ▸ | PPARG | P37231 | 7/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.45 |
| ▸ | MTTP | P55157 | 2/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3426982 | 0.91 | PPARA (0.42) | PTGDR2PPARAPPARDPPARGPSEN1 | |
| SCHEMBL3433773 | 0.89 | PPARA (0.43) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL15021253 | 0.87 | ITGB1 (0.41) | PTGDR2PPARAPPARDPPARGPSEN1 | |
| SCHEMBL3433349 | 0.82 | PPARA (0.37) | PTGDR2PPARAPPARDPPARGPSEN1 | |
| SCHEMBL3433469 | 0.80 | PPARA (0.40) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL150878 | 0.77 | PTGDR2 (0.60) | PTGDR2PPARAPPARGPSEN1PSEN2 | |
| SCHEMBL27985763 | 0.77 | PTPN1 (0.43) | PTGDR2PPARAPPARG | |
| SCHEMBL1235425 | 0.76 | PTGDR2 (0.63) | PTGDR2PPARAPPARDPPARG | |
| SCHEMBL138451 | 0.75 | PTGDR2 (0.62) | PTGDR2 | |
| SCHEMBL3411869 | 0.74 | PTGDR2 (0.43) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245002-A1 | N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | Amira Pharmaceuticals, Inc. (US) | 2010-11-03 | — | — | EP | claimed |
| WO-2009099901-A1 | N,N-DISUBSTITUTED AMINOALKYLBIPHENYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | claimed |