SCHEMBL3396545

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2790694	0.95	MC4R (0.55)	MC4RHSD11B1ALDH1A1KMT2ALMNA
	SCHEMBL2796032	0.84	HSD11B1 (0.71)	HSD11B1ALDH1A1KMT2ALMNASMN1; SMN2
	SCHEMBL14289421	0.82	HSD11B1 (0.79)	HSD11B1ALDH1A1KMT2ALMNAOPRM1
	SCHEMBL18390864	0.82	HSD11B1 (0.73)	HSD11B1ALDH1A1KMT2ALMNAOPRM1
	SCHEMBL18390860	0.79	MEN1 (0.74)	HSD11B1ALDH1A1KMT2ALMNAOPRM1
	SCHEMBL18390861	0.79	MEN1 (0.69)	HSD11B1ALDH1A1KMT2ALMNAOPRM1
	SCHEMBL8231613	0.79	HSD11B1 (0.59)	HSD11B1ALDH1A1KMT2ALMNAOPRM1
	SCHEMBL2796409	0.78	CYP2D6 (0.49)	HSD11B1ALDH1A1KMT2ALMNAOPRM1
	SCHEMBL13808570	0.78	ALDH1A1 (0.65)	MC4RHSD11B1ALDH1A1KMT2ALMNA
	SCHEMBL5330651	0.78	CYP2D6 (0.61)	ALDH1A1KMT2ALMNAOPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.