Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 8/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1239264 | 1.00 | DPP4 (0.49) | DPP4ACEHTR1AHTR7ALDH1A1 | |
| SCHEMBL670375 | 1.00 | DPP4 (0.49) | DPP4ACEHTR1AHTR7ALDH1A1 | |
| SCHEMBL22481429 | 0.95 | DPP4 (0.45) | DPP4ACEHTR1AHTR7 | |
| SCHEMBL6168040 | 0.89 | ALDH1A1 (0.41) | DPP4HTR1AHTR7ALDH1A1LMNA | |
| SCHEMBL8772871 | 0.83 | DPP4 (0.56) | DPP4ACEHTR1AHTR7 | |
| SCHEMBL1170836 | 0.83 | ACE (0.62) | ACELMNA | |
| SCHEMBL1493753 | 0.83 | DPP4 (0.47) | DPP4ACEHTR1AHTR7 | |
| SCHEMBL20839701 | 0.83 | ACE (0.62) | ACELMNA | |
| SCHEMBL8772866 | 0.83 | DPP4 (0.56) | DPP4ACEHTR1AHTR7 | |
| SCHEMBL3200494 | 0.83 | ACE (0.62) | ACELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022690-A2 | A METHOD OF PREPARATION OF HIGHLY PURE VILDAGLIPTIN | ZENTIVA, K.S. (CZ) | 2010-03-04 | — | — | WO | claimed |
| WO-2010022690-A2 | A METHOD OF PREPARATION OF HIGHLY PURE VILDAGLIPTIN | ZENTIVA, K.S. (CZ) | 2010-03-04 | — | — | WO | disclosed |