⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17337956 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL10382285 | 0.70 | — | — | |
| SCHEMBL8011185 | 0.63 | ALDH1A1 (0.46) | — | |
| SCHEMBL30031817 | 0.63 | CYP11B1 (0.36) | — | |
| SCHEMBL647672 | 0.63 | — | — | |
| SCHEMBL852350 | 0.62 | EDNRB (0.33) | — | |
| Hydrochloric Acid SCHEMBL6448210 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL645056 | 0.62 | — | — | |
| SCHEMBL11052520 | 0.62 | POLB (0.40) | — | |
| Hydrochloric Acid SCHEMBL4068961 | 0.62 | CYP11B1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097619-B2 | Inhibitors of cyclin-dependent kinases, compositions and uses related thereto | AGENNIX USA INC. (US) | 2012-01-17 | — | — | US | disclosed |
| US-7893057-B2 | Inhibitors of cyclin-dependent kinases, compositions and uses related thereto | AGENNIX USA INC. (US) | 2011-02-22 | — | — | US | disclosed |
| US-7786112-B2 | Inhibitors of cyclin-dependent kinases, compositions and uses related thereto | AGENNIX USA INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-20100004207-A1 | Inhibitors of cyclin-dependent kinases, compositions and uses related thereto | GPC BIOTECH INC. | 2010-01-07 | — | — | US | disclosed |
| US-7605175-B2 | Inhibitors of cyclin-dependent kinases, compositions and uses related thereto | GPC BIOTECH AG (DE) | 2009-10-20 | — | — | US | disclosed |
| US-20090209530-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES, COMPOSITIONS AND USES RELATED THERETO | GPC BIOTECH, INC. (US) | 2009-08-20 | — | — | US | disclosed |
| EP-1832589-A1 | Inhibitors of cyclin-dependent kinases,compositions and uses related thereto | GPC Biotech Inc. (US) | 2007-09-12 | — | — | EP | disclosed |
| EP-1709051-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES, COMPOSITIONS AND USES RELATED THERETO | GPC Biotech Inc. (US) | 2006-10-11 | — | — | EP | disclosed |
| EP-1611136-A2 | INHIBITORS OF CYCLIN-DEPENDENT KINASES, COMPOSITIONS AND USES RELATED THERETO | GPC Biotech Inc. (US) | 2006-01-04 | — | — | EP | disclosed |
| WO-2005063765-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES, COMPOSITIONS AND USES RELATED THERETO | GPC BIOTECH, INC. (US) | 2005-07-14 | — | — | WO | disclosed |
| US-20050090471-A1 | Inhibitors of cyclin-dependent kinases, compositions and uses related thereto | GPC BIOTECH, INC (US) | 2005-04-28 | — | — | US | disclosed |
| US-20040266854-A1 | Inhibitors of cyclin-dependent kinases, compositions and uses related thereto | GPC BIOTECH, INC. (US) | 2004-12-30 | — | — | US | disclosed |
| US-20040266853-A1 | Inhibitors of cyclin-dependent kinases, compositions and uses related thereto | GPC BIOTECH, INC. (US) | 2004-12-30 | — | — | US | disclosed |
| WO-2004092139-A2 | INHIBITORS OF CYCLIN-DEPENDENT KINASES, COMPOSITIONS AND USES RELATED THERETO | GPC BIOTECH, INC. (US) | 2004-10-28 | — | — | WO | disclosed |
| EP-1446405-A2 | INHIBITORS OF CYCLIN-DEPENDENT KINASES, COMPOSITIONS AND USES RELATED THERETO | GPC Biotech Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| US-6753329-B2 | 1,5-DIHYDROPYRAZOLO(3,4-D)PYRIMIDIN-4-ONE DERIVATIVES USEFUL FOR TRATING CANCER, TUMOR AND HYPERPROLIFERATIVE DISORDERS IN ANIMALS | GPC BIOTECH INC. | 2004-06-22 | — | — | US | disclosed |
| US-20030162797-A1 | Inhibitors of cyclin-dependent kinases, compositions and uses related thereto | GPC BIOTECH AG (DE) | 2003-08-28 | — | — | US | disclosed |
| WO-2003033499-A2 | INHIBITORS OF CYCLIN-DEPENDENT KINASES, COMPOSITIONS AND USES RELATED THERETO | GPC BIOTECH INC. (US) | 2003-04-24 | — | — | WO | disclosed |