⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7218919 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL8537113 | 0.98 | — | — | |
| SCHEMBL1355394 | 0.65 | — | — | |
| SCHEMBL15040620 | 0.63 | ALDH1A1 (0.38) | — | |
| SCHEMBL8472068 | 0.63 | ALDH1A1 (0.38) | — | |
| SCHEMBL23829741 | 0.63 | — | — | |
| SCHEMBL1353549 | 0.61 | GABRR1 (0.31) | — | |
| SCHEMBL23048514 | 0.61 | GABRR1 (0.31) | — | |
| SCHEMBL2301069 | 0.60 | — | — | |
| SCHEMBL31332023 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12233053-B2 | Adenosine A3 receptor antagonists for treating aging skin and wounds | ORADIN PHARMACEUTICAL LTD. (IL) | 2025-02-25 | — | — | US | claimed |
| EP-2229167-A1 | MINERALOCORTICOID RECEPTOR MODULATORS | Merck Sharp & Dohme Corp. (US) | 2010-09-22 | — | — | EP | claimed |
| WO-2009078934-A1 | MINERALOCORTICOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2009-06-25 | — | — | WO | claimed |
| EP-0225175-A2 | Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof | FISONS plc (GB) | 1987-06-10 | — | — | EP | claimed |
| US-20250179130-A1 | METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS | ON TARGET THERAPEUTICS LLC | 2025-06-05 | — | — | US | disclosed |
| US-20250101104-A1 | BISPECIFIC MOLECULE WITH TUNABLE AFFINITY TO A TARGETED ANTIGEN | MABSWITCH INC (US) | 2025-03-27 | — | — | US | disclosed |
| US-12060397-B2 | Soluble lipidated ligand agents for treating eye inflammation | TUFTS MEDICAL CENTER (US) | 2024-08-13 | — | — | US | disclosed |
| US-20240139205-A1 | MODULATORS OF ARALAR FOR TREATING NEUROLOGICAL DISORDERS | UNIVERSITE DE LAUSANNE (CH) | 2024-05-02 | — | — | US | disclosed |
| WO-2024069007-A2 | IMMUNOSUPPRESSIVE COMPOUNDS | UNIVERSITÄT BASEL (CH) | 2024-04-04 | — | — | WO | disclosed |
| EP-4175646-A1 | MODIFIED ADENOSINE NUCLEOSIDE FOR USE IN THE TREATMENT OF VIRAL INFECTIONS | Iachettini, Giampietro (IT) | 2023-05-10 | — | — | EP | disclosed |
| CN-115803033-A | Modified adenosine nucleosides for the treatment of viral infections | 詹皮特罗·亚切蒂尼 | 2023-03-14 | — | — | CN | disclosed |
| US-20220135633-A1 | METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS | ON TARGET THERAPEUTICS LLC | 2022-05-05 | — | — | US | disclosed |
| US-4994476-A | Hypotensive agents | BRISTOL-MYERS COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0371492-A2 | Process for the preparation of 1,4-dihydropyridine derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |
| EP-0324626-A1 | 1,4-Dihydropyridine derivatives | Korea Research Institute of Chemical Technology (KR) | 1989-07-19 | — | — | EP | disclosed |
| US-4769465-A | Process for the preparation of 2-(N-benzyl-N-methylamino)-ethyl methyl 2,6-dimethyl-4-(m-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate and its hydrochloride salt | LEK, TOVARNA FARMACEVTSKIH IN KEMICNIH IZDELKOV, N.SOL.O. (YU) | 1988-09-06 | — | — | US | disclosed |
| EP-0197488-A2 | 1,4-Dihydropyiridine derivative, a process for preparing the same, a pharmaceutical composition as well as the use thereof | Eisai Co., Ltd. (JP) | 1986-10-15 | — | — | EP | disclosed |
| EP-0161877-A2 | 1,4-dihydropyridine derivatives, methods for their production and pharmaceutical compositions comprising the same | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) | 1985-11-21 | — | — | EP | disclosed |
| US-4483985-A | ALKALINE HYDROLYSIS OF ESTER GROUP | BAYER AKTIENGESELLSCHAFT (DE) | 1984-11-20 | — | — | US | disclosed |
| US-4285955-A | CARDIOTONIC, HYPOTENSIVE, AND ANTISPASMOTIC AGENTS; VASODILATION | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-25 | — | — | US | disclosed |