Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718282 | 0.79 | GCGR (0.40) | CA12CA1CA2CA9RXFP1 | |
| SCHEMBL719032 | 0.73 | GCGR (0.38) | CNR2CNR1CA12CA1CA2 | |
| SCHEMBL14046923 | 0.69 | LOXL2 (0.39) | CNR2CNR1RXFP1PRNPKDM4E | |
| SCHEMBL718977 | 0.69 | MAPT (0.43) | CA1CA2RXFP1MAPTTP53 | |
| SCHEMBL13328626 | 0.67 | CNR1 (0.50) | CNR2CNR1RXFP1PRNPTAS1R3 | |
| SCHEMBL718054 | 0.67 | GCGR (0.58) | — | |
| SCHEMBL718249 | 0.67 | RCE1 (0.44) | CA12CA1CA2CA9RXFP1 | |
| SCHEMBL3638304 | 0.66 | HPGD (0.43) | CNR2CA1CA2RXFP1MAPT | |
| SCHEMBL720764 | 0.66 | RCE1 (0.46) | CA12CA1CA2CA9RXFP1 | |
| SCHEMBL31572047 | 0.66 | ALDH1A1 (0.69) | MAPTTP53KDM4ETDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2251326-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-11-17 | — | — | EP | disclosed |