Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.76 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | GAA | P10253 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13426215 | 0.89 | KIF11 (0.62) | KIF11PDE1CSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL3398042 | 0.89 | KIF11 (0.62) | KIF11PDE1CSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL13425966 | 0.89 | KIF11 (0.62) | KIF11PDE1CSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL3433120 | 0.88 | DHFR (0.64) | KIF11PDE1CSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL13425510 | 0.88 | PDE1C (0.74) | KIF11PDE1CSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL3394067 | 0.88 | PDE1C (0.59) | KIF11PDE1CSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL3391307 | 0.88 | MEN1 (0.79) | PDE1CGAAMEN1KMT2AADORA2B | |
| SCHEMBL3394451 | 0.88 | KIF11 (0.64) | KIF11PDE1CSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL3395577 | 0.88 | PDE1C (0.82) | KIF11PDE1CSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL3398285 | 0.88 | PDE1C (0.59) | KIF11PDE1CSMN1; SMN2NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |