Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 0.51 |
| ▸ | ACE | P12821 | 5/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14407783 | 1.00 | FKBP1A (0.51) | FKBP1AACECES2CES1 | |
| SCHEMBL3140080 | 1.00 | FKBP1A (0.51) | FKBP1AACECES2CES1 | |
| SCHEMBL5834349 | 1.00 | FKBP1A (0.51) | FKBP1AACECES2CES1 | |
| SCHEMBL14394666 | 0.98 | FKBP1A (0.49) | FKBP1AACE | |
| SCHEMBL5966183 | 0.96 | FKBP1A (0.55) | FKBP1AACECES2CES1 | |
| SCHEMBL14407780 | 0.96 | FKBP1A (0.55) | FKBP1AACECES2CES1 | |
| SCHEMBL14407787 | 0.96 | FKBP1A (0.55) | FKBP1AACECES2CES1 | |
| SCHEMBL14407782 | 0.96 | FKBP1A (0.55) | FKBP1AACECES2CES1 | |
| SCHEMBL14407795 | 0.96 | FKBP1A (0.55) | FKBP1AACECES2CES1 | |
| SCHEMBL14407789 | 0.95 | FKBP1A (0.52) | FKBP1AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242838-A1 | STEM-LIKE CELLS AND METHOD FOR REPROGRAMMING ADULT MAMMALIAN SOMATIC CELLS | GliaMed, Inc. (US) | 2010-10-27 | — | — | EP | claimed |
| WO-2009079007-A1 | STEM-LIKE CELLS AND METHOD FOR REPROGRAMMING ADULT MAMMALIAN SOMATIC CELLS | GLIAMED, INC. (US) | 2009-06-25 | — | — | WO | claimed |
| EP-1842845-A1 | Aza-heterocyclic compounds used to treat neurological disorders and hair loss | GliaMed, Inc. (US) | 2007-10-10 | — | — | EP | disclosed |
| US-7265150-B1 | Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds for vision and memory disorders | GPI NIL HOLDINGS INC. (US) | 2007-09-04 | — | — | US | disclosed |
| US-7265150-B1 | Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds for vision and memory disorders | GPI NIL HOLDINGS INC. (US) | 2007-09-04 | — | — | US | disclosed |
| EP-1127049-A1 | BRIDGED HETEROCYCLIC DERIVATIVES | GPI NIL Holdings, Inc. (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000016603-A2 | BRIDGED HETEROCYCLIC DERIVATIVES | GPI NIL HOLDINGS, INC. (US) | 2000-03-30 | — | — | WO | disclosed |
| US-5795908-A | FKBP IMMUNOPHILINS FOR ENZYME INHIBITORS | GPI NIL HOLDINGS, INC. (US) | 1998-08-18 | — | — | US | disclosed |