SCHEMBL339745

SCHEMBL339745

CCOP(=O)(Cc1ccccc1O)OCC

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
EGFR P00533 2/20 0.51
HSPA5 P11021 1/20 0.42
AKR1B1 P15121 1/20 0.41
POLB P06746 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
IDO1 P14902 2/20 0.40
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40
NR1I2 O75469 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
KCNH2 Q12809 1/20 0.40
PTPN2 P17706 1/20 0.39
PTPN1 P18031 1/20 0.39
HTR1A P08908 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL702504 0.87 NPSR1 (0.47) TSHREGFRPOLBNPSR1MAPT
SCHEMBL916250 0.86 TSHR (0.54) TSHREGFRHSPA5AKR1B1POLB
SCHEMBL915739 0.83 EGFR (0.47) TSHREGFRPOLBMEN1KMT2A
SCHEMBL11715486 0.83 TSHR (0.60) TSHR
SCHEMBL11710711 0.81 TSHR (0.53) TSHREGFRHSPA5AKR1B1IDO1
SCHEMBL8118478 0.81 TSHR (0.48) TSHREGFRHSPA5AKR1B1POLB
SCHEMBL14045287 0.80 TSHR (0.49) TSHRPOLBHTR1A
SCHEMBL916350 0.80 CCNT1 (0.43) TSHREGFRPOLBNPSR1MAPT
SCHEMBL12212067 0.80 NPSR1 (0.42) TSHREGFRPOLBNPSR1MAPT
SCHEMBL21259132 0.79 EGFR (0.55) TSHREGFRPOLBMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250298333-A1 POLYESTER RESIN COMPOSITION, ELECTROSTATIC CHARGE IMAGE DEVELOPING TONER, DEVELOPER, AND IMAGE FORMING METHOD Konica Minolta, Inc. (JP) 2025-09-25 US disclosed
US-11873315-B2 Chiral n-heterocyclic phosphorodiamidic acids (NHPAS) and derivatives as novel Brønsted acid catalysts THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) 2024-01-16 US disclosed
US-11873315-B2 Chiral n-heterocyclic phosphorodiamidic acids (NHPAS) and derivatives as novel Brønsted acid catalysts THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) 2024-01-16 US disclosed
US-11873315-B2 Chiral n-heterocyclic phosphorodiamidic acids (NHPAS) and derivatives as novel Brønsted acid catalysts THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) 2024-01-16 US disclosed
US-20220144868-A1 CHIRAL N-HETEROCYCLIC PHOSPHORODIAMIDIC ACIDS (NHPAS) AND DERIVATIVES AS NOVEL BRONSTED ACID CATALYSTS The Board of Regents of the Nevada System of Higher Education on Behalf of the Univ of Nevada (US) 2022-05-12 US disclosed
US-20220144868-A1 CHIRAL N-HETEROCYCLIC PHOSPHORODIAMIDIC ACIDS (NHPAS) AND DERIVATIVES AS NOVEL BRONSTED ACID CATALYSTS The Board of Regents of the Nevada System of Higher Education on Behalf of the Univ of Nevada (US) 2022-05-12 US disclosed
US-11248014-B2 Chiral n-heterocyclic phosphorodiamidic acids (NHPAS) and derivatives as novel bronsted acid catalysts THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) 2022-02-15 US disclosed
US-11248014-B2 Chiral n-heterocyclic phosphorodiamidic acids (NHPAS) and derivatives as novel bronsted acid catalysts THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) 2022-02-15 US disclosed
US-20210147457-A1 CHIRAL N-HETEROCYCLIC PHOSPHORODIAMIDIC ACIDS (NHPAS) AND DERIVATIVES AS NOVEL BRONSTED ACID CATALYSTS THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS 2021-05-20 US disclosed
US-20210147457-A1 CHIRAL N-HETEROCYCLIC PHOSPHORODIAMIDIC ACIDS (NHPAS) AND DERIVATIVES AS NOVEL BRONSTED ACID CATALYSTS THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS 2021-05-20 US disclosed
US-20070196750-A1 IMAGE BEARING MEMBER, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING THE SAME RICOH COMPANY, LIMITED. (JP) 2007-08-23 US disclosed
US-20070196749-A1 IMAGE BEARING MEMBER, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS RICOH COMPANY, LIMITED (JP) 2007-08-23 US disclosed
US-20070009818-A1 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-01-11 US disclosed
EP-1742112-A1 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor Ricoh Company, Ltd. (JP) 2007-01-10 EP disclosed
US-20060078809-A1 Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2006-04-13 US disclosed
US-6548042-B2 Such as tetraethyl-N-(m-trimethylsilylphenylethyl)amino-methylenebisphosphonate for palliative and curative treatment of bone disorders and breast cancer ARSTAD ERIK (NO) 2003-04-15 US disclosed
US-20020042539-A1 Bis-phosphonate compounds ARSTAD ERIK (NO) 2002-04-11 US disclosed
EP-0295729-B1 INTRAMOLECULAR NUCLEOPHILIC DISPLACEMENT COMPOUND AND USE IN PHOTOGRAPHY AGFA-GEVAERT N.V. (BE) 1991-09-04 EP disclosed
US-4912028-A Alkali permeable hydrophilic colloid AGFA-GEVAERT, N.V. (BE) 1990-03-27 US disclosed
EP-0295729-A1 Intramolecular nucleophilic displacement compound and use in photography AGFA-GEVAERT N.V. (BE) 1988-12-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210147457-A1 CHIRAL N-HETEROCYCLIC PHOSPHORODIAMIDIC ACIDS (NHPAS) AND DERIVATIVES AS NOVEL BRONSTED ACID CATALYSTS ELANE, PNKP, NHERF1 TSHR 3006/4885EGFR 2426/4885HSPA5 3993/4885
US-11248014-B2 Chiral n-heterocyclic phosphorodiamidic acids (NHPAS) and derivatives as novel bronsted acid catalysts ELANE, PNKP, NHERF1 TSHR 3006/4885EGFR 2426/4885HSPA5 3993/4885
US-20020042539-A1 Bis-phosphonate compounds PHOSPHO1, PTMS, PTEN TSHR 1944/4885EGFR 460/4885HSPA5 4038/4885
US-11873315-B2 Chiral n-heterocyclic phosphorodiamidic acids (NHPAS) and derivatives as novel Brønsted acid catalysts ELANE, PNKP, SERPINB1 TSHR 2516/4885EGFR 2498/4885HSPA5 4261/4885
US-20220144868-A1 CHIRAL N-HETEROCYCLIC PHOSPHORODIAMIDIC ACIDS (NHPAS) AND DERIVATIVES AS NOVEL BRONSTED ACID CATALYSTS ELANE, PNKP, NHERF1 TSHR 3006/4885EGFR 2426/4885HSPA5 3993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.