Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3398136 | 0.85 | XDH (0.54) | MAOBMAPTNPSR1PTGS1PTGS2 | |
| SCHEMBL13425770 | 0.80 | SMN1; SMN2 (0.55) | MAOBDHFRMAPTMAOA | |
| SCHEMBL6816900 | 0.78 | MAOB (0.59) | BACE1MAOBDHFRMAPTNPSR1 | |
| SCHEMBL2322961 | 0.78 | ADORA2A (0.50) | MAPTPIK3CGPRKDC | |
| SCHEMBL978442 | 0.78 | IGF1R (0.57) | BACE1MAOBDHFRMAPTNPSR1 | |
| SCHEMBL3395696 | 0.77 | ADORA2A (0.53) | DHFRMAPTGABRG2GABRB3GABRA5 | |
| SCHEMBL8598725 | 0.76 | ALDH1A1 (0.55) | BACE1MAOBDHFRMAPTNPSR1 | |
| Bromide SCHEMBL8359230 | 0.75 | ALDH1A1 (0.55) | BACE1MAOBMAPTNPSR1IGF1R | |
| SCHEMBL3397994 | 0.75 | IDO1 (0.50) | BACE1DHFRMAPTPIK3CA | |
| SCHEMBL379281 | 0.75 | MAOB (0.67) | MAOBMAOAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |