Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | OXTR | P30559 | 4/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369941 | 0.79 | OXTR (0.54) | CNR2KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3366190 | 0.79 | OXTR (0.54) | CNR2KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3369962 | 0.76 | OXTR (0.55) | CNR2KMT2AALDH1A1LMNAOXTR | |
| SCHEMBL5644407 | 0.75 | OXTR (0.57) | CNR2KMT2AALDH1A1LMNAOXTR | |
| SCHEMBL3366811 | 0.75 | KMT2A (0.47) | CNR2KMT2ALMNAOXTRAVPR1A | |
| SCHEMBL10356049 | 0.75 | CNR2 (0.51) | CNR2KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3367804 | 0.72 | KMT2A (0.48) | CNR2KMT2ALMNAOXTRAVPR1A | |
| SCHEMBL7141942 | 0.72 | OXTR (0.48) | CNR2KMT2AALDH1A1LMNAOXTR | |
| SCHEMBL5333494 | 0.71 | ALDH1A1 (0.58) | CNR2KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3365552 | 0.71 | MAPT (0.62) | KMT2AALDH1A1LMNAOXTRAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335901-B1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | MERCK SERONO SA (CH) | 2010-04-14 | — | — | EP | claimed |