Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 7/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | JAK3 | P52333 | 2/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13425393 | 0.86 | CYP11B2 (0.47) | NUDT1ADORA2AADORA1TLR8JAK3 | |
| SCHEMBL3398225 | 0.82 | ADORA2A (0.49) | NUDT1ADORA2AADORA1TLR8FGFR1 | |
| SCHEMBL13425671 | 0.75 | ATR (0.46) | ADORA2AADORA1TLR8CDC7CDK2 | |
| SCHEMBL18672504 | 0.75 | NUDT1 (0.68) | NUDT1ADORA2ATLR8FGFR1JAK3 | |
| SCHEMBL31155969 | 0.75 | NUDT1 (0.48) | NUDT1TLR8FGFR1JAK3CDC7 | |
| SCHEMBL20619965 | 0.75 | NUDT1 (0.68) | NUDT1TLR8FGFR1JAK3CDC7 | |
| SCHEMBL27208074 | 0.74 | CNR2 (0.40) | NUDT1TLR8CNR2CYP11B2PIK3CD | |
| SCHEMBL3395606 | 0.73 | ADORA2A (0.44) | ADORA2AADORA1TLR8FGFR1 | |
| SCHEMBL3398943 | 0.73 | ADORA2A (0.44) | ADORA2AADORA1TLR8 | |
| SCHEMBL2324805 | 0.72 | MPL (0.50) | ADORA2AADORA1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |