Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 2/20 | 0.34 |
| ▸ | FNTB | P49356 | 2/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3398420 | 0.88 | KCNH2 (0.42) | KCNH2LRRK2RAB9A | |
| SCHEMBL3427227 | 0.87 | KCNH2 (0.42) | KCNH2LRRK2FYN | |
| SCHEMBL3399143 | 0.87 | KCNH2 (0.41) | KCNH2LRRK2RAB9A | |
| SCHEMBL3432960 | 0.85 | KCNH2 (0.43) | KCNH2LRRK2 | |
| SCHEMBL3434686 | 0.84 | KCNH2 (0.44) | KCNH2LRRK2ALDH1A1GSK3BGSK3A | |
| SCHEMBL3432594 | 0.84 | KCNH2 (0.40) | KCNH2LRRK2FYN | |
| Hydrochloric Acid SCHEMBL3432843 | 0.84 | KCNH2 (0.42) | KCNH2LRRK2 | |
| Hydrochloric Acid SCHEMBL3395604 | 0.84 | KCNH2 (0.43) | KCNH2LRRK2ALDH1A1GSK3BGSK3A | |
| SCHEMBL3392940 | 0.83 | LMNA (0.41) | KCNH2KDM4EALDH1A1GAA | |
| SCHEMBL3396008 | 0.82 | TNIK (0.43) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |