Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393634 | 0.91 | KCNH2 (0.39) | LMNAKCNH2ALDH1A1MAPTMEN1 | |
| SCHEMBL3395956 | 0.85 | MAPT (0.41) | LMNAKCNH2KDM4EALDH1A1GAA | |
| SCHEMBL3427227 | 0.85 | KCNH2 (0.42) | KCNH2ADRA2AADRA2BADRA2C | |
| SCHEMBL3397552 | 0.83 | KCNH2 (0.43) | KCNH2KDM4EALDH1A1GAA | |
| SCHEMBL3432960 | 0.83 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL3434686 | 0.82 | KCNH2 (0.44) | KCNH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3432843 | 0.82 | KCNH2 (0.42) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3395604 | 0.81 | KCNH2 (0.43) | KCNH2ALDH1A1 | |
| SCHEMBL3392938 | 0.81 | KCNH2 (0.54) | LMNAKCNH2AKR1C3AKR1C2KDM4E | |
| SCHEMBL3426389 | 0.80 | KCNH2 (0.43) | KCNH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |