Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.47 |
| ▸ | DCUN1D2 | Q6PH85 | 1/20 | 0.47 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | LTK | P29376 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29499607 | 1.00 | DCUN1D1 (0.47) | DCUN1D1DCUN1D2NISCHMETAP2AKT1 | |
| SCHEMBL29034386 | 0.96 | DCUN1D1 (0.45) | DCUN1D1DCUN1D2NISCHMETAP2AKT1 | |
| SCHEMBL12615990 | 0.89 | ALDH1A1 (0.38) | DCUN1D1DCUN1D2ALDH1A1 | |
| Benzylamine SCHEMBL27675029 | 0.87 | DPP4 (0.43) | DCUN1D1DCUN1D2METAP2AKT2LMNA | |
| Methylbiphenyl Tetrazole SCHEMBL1774035 | 0.85 | NR1H2 (0.39) | DCUN1D1DCUN1D2LMNAALDH1A1HPGD | |
| SCHEMBL8035241 | 0.85 | KDR (0.41) | DCUN1D1DCUN1D2AKT1LMNAMAP4K4 | |
| SCHEMBL4794234 | 0.85 | DCUN1D1 (0.36) | DCUN1D1DCUN1D2 | |
| SCHEMBL9155822 | 0.85 | ABL1 (0.47) | DCUN1D1DCUN1D2HSD17B10BCL2L1NPC1 | |
| SCHEMBL4712959 | 0.85 | DCUN1D1 (0.36) | DCUN1D1DCUN1D2NISCH | |
| Methylbiphenyl Tetrazole SCHEMBL29457258 | 0.85 | NR1H2 (0.39) | DCUN1D1DCUN1D2LMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9724673-B2 | Supported alkoxylated organotin reactant, preparation and use for heterogeneous-phase synthesis of tetrazoles | UNIVERSITE DE NANTES (FR) | 2017-08-08 | — | — | US | claimed |
| EP-2726515-B1 | SUPPORTED ALKOXYLATED ORGANOTIN REACTANT, PREPARATION AND USE FOR HETEROGENEOUS-PHASE SYNTHESIS OF TETRAZOLES | CENTRE NAT RECH SCIENT (FR) | 2015-04-01 | — | — | EP | claimed |
| US-20140206825-A1 | SUPPORTED ALKOXYLATED ORGANOTIN REACTANT, PREPARATION AND USE FOR HETEROGENEOUS-PHASE SYNTHESIS OF TETRAZOLES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2014-07-24 | — | — | US | claimed |
| JP-2005538152-A | — | — | 2005-12-15 | — | — | JP | claimed |
| EP-1537075-A2 | DIARYLUREA DERIVATIVES AND THEIR USE AS CHLORIDE CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 2005-06-08 | — | — | EP | claimed |
| WO-2004022529-A2 | DIARYLUREA DERIVATIVES AND THEIR USE AS CHLORIDE CHANNEL BLOCKERS | NEUROSEARCH A/S (DK) | 2004-03-18 | — | — | WO | claimed |
| JP-3098772-B2 | — | — | 2000-10-16 | — | — | JP | claimed |
| EP-0527851-A1 | 1H-SUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1993-02-24 | — | — | EP | claimed |
| WO-1991017148-A1 | 1H-SUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-11-14 | — | — | WO | claimed |
| JP-5155884-A | — | — | None | — | — | JP | disclosed |
| JP-5271205-A | — | — | None | — | — | JP | disclosed |
| CN-117672401-A | Structure-activity relation model for predicting acute oral toxicity of tetrazole compound mice and construction method | 兵器工业卫生研究所 | 2024-03-08 | — | — | CN | disclosed |
| CN-111592500-A | ARB-NEPi compound, crystal form, preparation method and application | 上海博志研新药物技术有限公司 | 2020-08-28 | — | — | CN | disclosed |
| US-9724673-B2 | Supported alkoxylated organotin reactant, preparation and use for heterogeneous-phase synthesis of tetrazoles | UNIVERSITE DE NANTES (FR) | 2017-08-08 | — | — | US | disclosed |
| EP-0550313-A1 | 2-(Tetranol-5-yl)-(1,1'-biphenyl)derivatives, their preparation and use as intermediates | SYNTHELABO (FR) | 1993-07-07 | — | — | EP | disclosed |
| JP-H05155884-A | CONDENSED PIRAZINE DERIVATIVE | KYOWA HAKKO KOGYO CO LTD | 1993-06-22 | — | — | JP | disclosed |
| WO-1993008169-A1 | SUBSTITUTED AMINOPYRIMIDINES AS ANGIOTENSINE II ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-04-29 | — | — | WO | disclosed |
| EP-0531382-A1 | N-SUBSTITUTED-1,2,4-TRIAZOLONE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1993-03-17 | — | — | EP | disclosed |
| WO-1991018888-A1 | N-SUBSTITUTED-1,2,4-TRIAZOLONE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1991-12-12 | — | — | WO | disclosed |
| CN-1048546-A | Substituted imidazo-fused 6 unit heterocycle as angiotensin II antagonism medicine | MERCK & CO INC (US) | 1991-01-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140206825-A1 | SUPPORTED ALKOXYLATED ORGANOTIN REACTANT, PREPARATION AND USE FOR HETEROGENEOUS-PHASE SYNTHESIS OF TETRAZOLES | ALK, TST, TEKT1 | DCUN1D1 991/4885DCUN1D2 1099/4885NISCH 334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.