Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12803300 | 0.84 | TACR1 (0.40) | LIPGLPL | |
| SCHEMBL25425656 | 0.80 | LIPG (0.40) | LIPGLPLKMT2AMEN1ALDH1A1 | |
| SCHEMBL15639975 | 0.79 | CHRM3 (0.34) | — | |
| SCHEMBL20893524 | 0.77 | ROCK1 (0.38) | ROCK1 | |
| SCHEMBL1363539 | 0.77 | USP30 (0.48) | LIPGLPLGAALMNASMN1; SMN2 | |
| SCHEMBL16101170 | 0.76 | F2 (0.33) | LIPGROCK1 | |
| SCHEMBL1362568 | 0.76 | LIPG (0.50) | LIPGLPLCCR3LMNASMN1; SMN2 | |
| SCHEMBL13700132 | 0.75 | LIPG (0.57) | LIPGLPLROCK1 | |
| SCHEMBL2549987 | 0.74 | CCR3 (0.40) | CCR3KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL3478584 | 0.74 | NR1H2 (0.39) | ROCK1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2249830-A1 | DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS | Glaxo Group Limited (GB) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009100170-A1 | DUAL PHARMACOPHORES - PDE4-MUSCARINIC ANTAGONISTICS | GLAXO GROUP LIMITED (GB) | 2009-08-13 | — | — | WO | disclosed |