Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.40 |
| ▸ | LPL | P06858 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399142 | 0.87 | LIPG (0.42) | LIPGLPLOPRM1OPRK1MEN1 | |
| SCHEMBL3399375 | 0.87 | LIPG (0.42) | LIPGLPLOPRM1OPRK1MEN1 | |
| SCHEMBL1363050 | 0.87 | LIPG (0.39) | LIPGLPLAGTR2OPRM1OPRK1 | |
| SCHEMBL3045151 | 0.82 | LIPG (0.47) | LIPGLPLKDM4EALDH1A1MEN1 | |
| SCHEMBL31123835 | 0.81 | F11 (0.35) | LIPGLPLALDH1A1KMT2A | |
| SCHEMBL3478584 | 0.81 | NR1H2 (0.39) | ROCK1 | |
| SCHEMBL8020161 | 0.80 | USP30 (0.40) | LIPGLPL | |
| SCHEMBL1363047 | 0.80 | USP30 (0.40) | LIPGLPL | |
| SCHEMBL3397755 | 0.80 | LIPG (0.39) | LIPGLPLALDH1A1MEN1KMT2A | |
| SCHEMBL3773661 | 0.79 | AGTR2 (0.50) | AGTR2KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023140629-A1 | 2,7-SUBSTITUTED PYRROLO[2,1-F][1,2,4]TRIAZINE COMPOUND HAVING PROTEIN KINASE INHIBITORY ACTIVITY | 닥터아이앤비(주) | 2023-07-27 | — | — | WO | disclosed |