Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14907043 | 0.85 | CA1 (0.66) | NPC1RAB9AALDH1A1KDM4EPOLB | |
| SCHEMBL4762283 | 0.85 | HPGD (0.61) | NPC1RAB9AALDH1A1KDM4EPOLB | |
| SCHEMBL3140037 | 0.84 | HPGD (0.64) | NPC1RAB9AALDH1A1KDM4EPOLB | |
| SCHEMBL6651792 | 0.81 | HPGD (0.53) | NPC1RAB9AALDH1A1KDM4EPOLB | |
| SCHEMBL30320291 | 0.81 | HPGD (0.53) | NPC1RAB9AALDH1A1KDM4EPOLB | |
| SCHEMBL29231950 | 0.80 | HPGD (0.66) | NPC1RAB9AALDH1A1KDM4EPOLB | |
| SCHEMBL16358867 | 0.79 | CA1 (0.73) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL29191662 | 0.79 | SMN1; SMN2 (0.62) | NPC1RAB9AALDH1A1KDM4EPOLB | |
| SCHEMBL9818531 | 0.78 | ALDH1A1 (0.77) | NPC1RAB9AALDH1A1KDM4EPOLB | |
| SCHEMBL12903506 | 0.78 | ALDH1A1 (0.56) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114656423-A | Preparation method of 4-methyl-2-hydrazinobenzothiazole hydrochloride | 浙江南郊化学有限公司 | 2022-06-24 | — | — | CN | claimed |
| CN-111333593-B | Method for synthesizing 4-methyl-2 hydrazinobenzothiazole | 湖北可赛化工有限公司 | 2022-04-29 | — | — | CN | claimed |
| CN-111333593-A | Method for synthesizing 4-methyl-2 hydrazinobenzothiazole | 湖北可赛化工有限公司 | 2020-06-26 | — | — | CN | claimed |
| CN-114656423-A | Preparation method of 4-methyl-2-hydrazinobenzothiazole hydrochloride | 浙江南郊化学有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-114656423-A | Preparation method of 4-methyl-2-hydrazinobenzothiazole hydrochloride | 浙江南郊化学有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-111333593-B | Method for synthesizing 4-methyl-2 hydrazinobenzothiazole | 湖北可赛化工有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-111333593-B | Method for synthesizing 4-methyl-2 hydrazinobenzothiazole | 湖北可赛化工有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-211814216-U | System for recycling o-toluidine in waste liquid generated in preparation of N-o-tolylthiourea | 山西瑞赛科环保科技有限公司 | 2020-10-30 | — | — | CN | disclosed |
| CN-111333593-A | Method for synthesizing 4-methyl-2 hydrazinobenzothiazole | 湖北可赛化工有限公司 | 2020-06-26 | — | — | CN | disclosed |
| CN-111333593-A | Method for synthesizing 4-methyl-2 hydrazinobenzothiazole | 湖北可赛化工有限公司 | 2020-06-26 | — | — | CN | disclosed |
| CN-101129295-B | There is the binary initiator system of good storage stability and especially suitable for acidic system | HERAEUS KULZER GMBH (DE) | 2016-02-10 | — | — | CN | disclosed |
| WO-2011022393-A2 | PHOSPHATIDYLCHOLINE TRANSFER PROTEIN INHIBITORS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2011-02-24 | — | — | WO | disclosed |
| US-20100324096-A1 | Whitening Agent And Skin External Preparation | SHISEIDO COMPANY LTD. (JP) | 2010-12-23 | — | — | US | disclosed |
| EP-2251001-A1 | SKIN WHITENING AGENT AND EXTERNAL PREPARATION FOR THE SKIN | Shiseido Company, Ltd. (JP) | 2010-11-17 | — | — | EP | disclosed |
| CN-101129295-A | 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems | HERAEUS KULZER GMBH (DE) | 2008-02-27 | — | — | CN | disclosed |
| CN-85109721-A | Preparation has the ectoparasite of the no disease homoiothermic animal of control and the method for endoparasite compositions | — | 1987-07-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324096-A1 | Whitening Agent And Skin External Preparation | TYR, MC1R, PAH | NPC1 3805/4885RAB9A 2964/4885ALDH1A1 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.