SCHEMBL4762283

SCHEMBL4762283

Cc1ccccc1C(=O)NC(N)=O

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.61
SMN1; SMN2 Q16637 3/20 0.56
TYK2 P29597 1/20 0.54
ALDH1A1 P00352 2/20 0.54
POLB P06746 3/20 0.53
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
KDM4E B2RXH2 1/20 0.51
SCN5A Q14524 1/20 0.51
SCN2A Q99250 1/20 0.51
DHODH Q02127 1/20 0.50
KCNK3 O14649 1/20 0.50
KCNK9 Q9NPC2 1/20 0.50
LMNA P02545 1/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C19 P33261 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3140037 0.87 HPGD (0.64) HPGDSMN1; SMN2TYK2ALDH1A1POLB
SCHEMBL6651792 0.85 HPGD (0.53) HPGDSMN1; SMN2TYK2ALDH1A1POLB
SCHEMBL3397939 0.85 NPC1 (0.60) HPGDSMN1; SMN2ALDH1A1POLBNPC1
SCHEMBL30320291 0.85 HPGD (0.53) HPGDSMN1; SMN2TYK2ALDH1A1POLB
SCHEMBL27928537 0.85 NPC1 (0.48) HPGDSMN1; SMN2ALDH1A1POLBNPC1
SCHEMBL29231950 0.83 HPGD (0.66) HPGDSMN1; SMN2TYK2ALDH1A1POLB
SCHEMBL29191662 0.82 SMN1; SMN2 (0.62) HPGDSMN1; SMN2TYK2ALDH1A1POLB
SCHEMBL11589554 0.82 ALDH1A1 (0.42) HPGDSMN1; SMN2ALDH1A1POLBNPC1
O-Xylene SCHEMBL28216592 0.81 POLB (0.62) HPGDSMN1; SMN2ALDH1A1POLBNPC1
SCHEMBL1068505 0.80 HPGD (0.49) HPGDSMN1; SMN2TYK2ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080280988-A1 Use of (N'-Methyl) benzoylurea compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-11-13 US claimed
US-20080274884-A1 Novel use of (N'-methyl)benzoylurea compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-11-06 US claimed
US-20080280988-A1 Use of (N'-Methyl) benzoylurea compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-11-13 US disclosed
US-20080280988-A1 Use of (N'-Methyl) benzoylurea compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-11-13 US disclosed
JP-2008266188-A USE OF (N'-METHYL)BENZOYL UREA COMPOUND SUMITOMO CHEMICAL CO LTD 2008-11-06 JP disclosed
JP-2008266187-A USE OF (N'-METHYL)BENZOYL UREA COMPOUND SUMITOMO CHEMICAL CO LTD 2008-11-06 JP disclosed
US-20080274884-A1 Novel use of (N'-methyl)benzoylurea compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-11-06 US disclosed
US-20080274884-A1 Novel use of (N'-methyl)benzoylurea compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-11-06 US disclosed
US-20080274884-A1 Novel use of (N'-methyl)benzoylurea compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-11-06 US disclosed
JP-2007297375-A METHOD FOR PROTECTING PLANT SUMITOMO CHEMICAL CO LTD 2007-11-15 JP disclosed
WO-2007116949-A1 PLANT PROTECTION METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-18 WO disclosed
WO-2007116948-A1 PLANT PROTECTION METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-18 WO disclosed
CN-85109721-A Preparation has the ectoparasite of the no disease homoiothermic animal of control and the method for endoparasite compositions 1987-07-15 CN disclosed
CN-86100630-A Preparation contains the method for the sterilant of acylurea 1986-09-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080274884-A1 Novel use of (N'-methyl)benzoylurea compound RNGTT, L3MBTL4, MYB HPGD 4744/4885SMN1; SMN2 820/4885TYK2 3463/4885
US-20080280988-A1 Use of (N'-Methyl) benzoylurea compound L3MBTL4, L3MBTL3, L3MBTL1 HPGD 4558/4885SMN1; SMN2 2295/4885TYK2 4401/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.