⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL163290 | 0.74 | — | — | |
| SCHEMBL23320098 | 0.73 | — | — | |
| SCHEMBL1044057 | 0.73 | — | — | |
| SCHEMBL22341260 | 0.72 | SCN4A (0.61) | — | |
| SCHEMBL14857340 | 0.72 | KDM4E (0.33) | — | |
| SCHEMBL2725546 | 0.72 | MAPT (0.44) | — | |
| Hydrochloric Acid SCHEMBL11557202 | 0.71 | NOS1 (0.53) | — | |
| SCHEMBL12080331 | 0.70 | ALOX15 (0.40) | — | |
| SCHEMBL23068529 | 0.69 | FYN (0.41) | — | |
| SCHEMBL22490559 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021150574-A1 | SULFONIMIDAMIDE COMPOUNDS AS NLRP3 MODULATORS | GENENTECH, INC. (US) | 2021-07-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |