Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.49 |
| ▸ | NOS2 | P35228 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 7/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRND | Q07001 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27959725 | 0.81 | SMN1; SMN2 (0.47) | MAPTRAB9ASYK | |
| SCHEMBL7485139 | 0.80 | SGMS2 (0.51) | CHRNB2CHRNA4MAPTRAB9ANPSR1 | |
| SCHEMBL23456171 | 0.80 | F2 (0.52) | MAPTRAB9A | |
| SCHEMBL6079140 | 0.78 | RAB9A (0.57) | NOS1NOS2CHRNB2CHRNA4MAPT | |
| SCHEMBL27606001 | 0.77 | HDAC3 (0.37) | SYK | |
| SCHEMBL28492679 | 0.76 | ORAI1 (0.49) | NOS1NOS2CHRNB2CHRNA4MAPT | |
| SCHEMBL1323646 | 0.75 | RAB9A (0.62) | NOS1NOS2CHRNB2CHRNA4MAPT | |
| SCHEMBL30150593 | 0.75 | RAB9A (0.62) | NOS1NOS2CHRNB2CHRNA4MAPT | |
| SCHEMBL18906044 | 0.75 | TP53 (0.51) | MAPTRAB9ANPSR1DAO | |
| SCHEMBL27625101 | 0.75 | MAPT (0.61) | NOS1NOS2CHRNB2CHRNA4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777131-B | Synthesis method of paliperidone and key intermediate thereof | 合肥华方医药科技有限公司 | 2024-06-11 | — | — | CN | claimed |
| CN-117777131-A | Synthesis method of paliperidone and key intermediate thereof | 合肥华方医药科技有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-102797043-A | Medicinal molecular fragment library and construction method thereof | CBB NETWORK CO LTD | 2012-11-28 | — | — | CN | claimed |
| CN-1164568-C | Process for condensating salicyladehyde with arylamine | 中国科学院化学研究所 | 2004-09-01 | — | — | CN | claimed |
| CN-1139606-C | Norbornene catalytic system and its preparation method and application | 中国科学院化学研究所 | 2004-02-25 | — | — | CN | claimed |
| CN-1394685-A | Norbornene catalytic system and its preparation method and application | CHINESE ACAD INST CHEMISTRY (CN) | 2003-02-05 | — | — | CN | claimed |
| CN-1386735-A | Process for condensating salicyladehyde with arylamine | CHINESE ACAD INST CHEMISTRY (CN) | 2002-12-25 | — | — | CN | claimed |
| CN-117777131-B | Synthesis method of paliperidone and key intermediate thereof | 合肥华方医药科技有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-117777131-B | Synthesis method of paliperidone and key intermediate thereof | 合肥华方医药科技有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-118027038-A | Hydrogen-bond-assisted chiral dicycloimidazole organic micromolecular catalyst and synthesis method thereof | 上海交通大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-117777131-A | Synthesis method of paliperidone and key intermediate thereof | 合肥华方医药科技有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117777131-A | Synthesis method of paliperidone and key intermediate thereof | 合肥华方医药科技有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-103265477-A | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN INC | 2013-08-28 | — | — | CN | disclosed |
| US-5409943-A | [(alkoxy)pyridinyl]amine compounds which are useful in the treatment of gastrointestinal disorders | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1995-04-25 | — | — | US | disclosed |
| EP-0625143-A1 | PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICINES | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1994-11-23 | — | — | EP | disclosed |
| CN-1076197-A | The preparation method of indole urea derivative | BEECHAM GROUP PLC (GB) | 1993-09-15 | — | — | CN | disclosed |
| WO-1993015055-A1 | PYRIDINE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICINES | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1993-08-05 | — | — | WO | disclosed |
| CN-86104313-A | The preparation method of Imidazoheterocyclic compounds | — | 1987-03-04 | — | — | CN | disclosed |
| CN-85105797-A | The preparation of antimicrobial compounds | — | 1986-08-27 | — | — | CN | disclosed |
| US-4450164-A | ANTIULCER AND ANTISECRETORY AGENTS | SCHERING CORPORATION (US) | 1984-05-22 | — | — | US | disclosed |