Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.74 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.74 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.74 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.63 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.58 |
| ▸ | LIPE | Q05469 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL27839739 | 0.96 | HTR1A (0.70) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL339812 | 0.89 | MAPT (0.71) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL23582260 | 0.86 | HTR1A (0.59) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL29914010 | 0.86 | HTR1A (0.59) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL10607164 | 0.86 | HTR1A (0.58) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL10796837 | 0.84 | KDM4E (0.60) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL12584881 | 0.84 | KDM4E (0.57) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL12251449 | 0.84 | MEN1 (0.63) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| 1,2-Diethoxybenzene SCHEMBL578986 | 0.83 | ALDH1A1 (0.68) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL15922822 | 0.83 | HTR1A (0.65) | HTR1AADRA1DADRA1AADRA1BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056497-A1 | AMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2010-03-04 | — | — | US | disclosed |
| US-20100056497-A1 | AMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056497-A1 | AMIDE DERIVATIVE | REN, AGTR1, AGTR2 | HTR1A 993/4885ADRA1D 12/4885ADRA1A 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.