Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.62 |
| ▸ | BCL9 | O00512 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | Q9HBH1 | 1/20 | 0.44 | |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27677380 | 0.88 | MGLL (0.49) | MGLLBCL9CTNNB1TGM2PPARG | |
| SCHEMBL30544863 | 0.87 | TGM2 (0.50) | MGLLBCL9CTNNB1TGM2PPARG | |
| SCHEMBL26915268 | 0.85 | FOLH1 (0.50) | MGLLBCL9CTNNB1TGM2PPARG | |
| SCHEMBL8477195 | 0.85 | FOLH1 (0.50) | MGLLBCL9CTNNB1TGM2PPARG | |
| SCHEMBL14996322 | 0.84 | MGLL (0.63) | MGLLBCL9CTNNB1ALDH1A1GAA | |
| SCHEMBL16762227 | 0.84 | MGLL (0.63) | MGLLBCL9CTNNB1ALDH1A1GAA | |
| SCHEMBL11145406 | 0.83 | TGM2 (0.68) | TGM2 | |
| SCHEMBL11139544 | 0.83 | TGM2 (0.68) | TGM2 | |
| SCHEMBL11139545 | 0.83 | TGM2 (0.68) | TGM2 | |
| SCHEMBL7488389 | 0.83 | MGLL (0.56) | MGLLBCL9CTNNB1TGM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250164-A2 | ANGIOTENSIN II RECEPTOR BLOCKER DERIVATIVES | Nicox S.A. (FR) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009106471-A2 | NEW ANGIOTENSIN II RECEPTOR BLOCKER DERIVATIVES | NICOX S.A. (FR) | 2009-09-03 | — | — | WO | disclosed |