Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 3/20 | 0.35 |
| ▸ | GHSR | Q92847 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718338 | 0.77 | BCHE (0.41) | BCHENOTUMADORA3ADORA1ADORA2A | |
| SCHEMBL719683 | 0.72 | BCHE (0.42) | BCHENOTUMADORA3ADORA1ADORA2A | |
| SCHEMBL719895 | 0.70 | MEN1 (0.50) | NOTUMADORA3ADORA1ADORA2ALMNA | |
| SCHEMBL720888 | 0.70 | HSD17B10 (0.59) | NOTUMADORA3ADORA1ADORA2ARORC | |
| SCHEMBL720453 | 0.68 | ALDH1A1 (0.52) | NOTUMADORA3ADORA1LMNATSHR | |
| SCHEMBL717877 | 0.67 | BCHE (0.42) | BCHENOTUMADORA3ADORA1ADORA2A | |
| SCHEMBL719334 | 0.65 | BCHE (0.40) | BCHENOTUMLMNATSHRMAPK1 | |
| SCHEMBL719184 | 0.65 | PDE4A (0.43) | BCHENOTUMLMNATSHRMAPK1 | |
| SCHEMBL718340 | 0.64 | IDO1 (0.41) | ADORA3RORCLMNAMEN1GFER | |
| SCHEMBL24908474 | 0.62 | BCHE (0.52) | BCHENOTUMKDM1ALMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2251326-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-11-17 | — | — | EP | disclosed |