SCHEMBL3398384

SCHEMBL3398384

CC1CCN(c2c(-c3c(F)cc(F)cc3F)cnc3ncnn23)CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
GLA P06280 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ALDH1A1 P00352 6/20 0.38
LMNA P02545 5/20 0.38
EGLN2 Q96KS0 1/20 0.36
MAPT P10636 5/20 0.35
TP53 P04637 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.34
GRM5 P41594 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
GAA P10253 1/20 0.33
PDE2A O00408 4/20 0.32
NPC1 O15118 2/20 0.32
HPGD P15428 2/20 0.32
RAB9A P51151 2/20 0.32
CASP3 P42574 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL868344 0.81 GRM5 (0.38) ALDH1A1LMNAMAPTTP53SMN1; SMN2
SCHEMBL4815038 0.80 TSHR (0.42) TSHRGLANPSR1ALDH1A1LMNA
SCHEMBL976406 0.80 LMNA (0.47) TSHRGLANPSR1ALDH1A1LMNA
SCHEMBL81282 0.79 TSHR (0.41) TSHRGLANPSR1ALDH1A1LMNA
SCHEMBL5460885 0.77 TSHR (0.40) TSHRGLANPSR1ALDH1A1LMNA
SCHEMBL5462930 0.77 EGLN2 (0.44) TSHRGLANPSR1ALDH1A1LMNA
SCHEMBL120876 0.74 TP53 (0.36) TSHRGLANPSR1ALDH1A1LMNA
SCHEMBL20439999 0.74 EGLN2 (0.42) TSHRGLANPSR1ALDH1A1LMNA
SCHEMBL14093691 0.73 ALDH1A1 (0.35) TSHRGLANPSR1ALDH1A1LMNA
SCHEMBL4157774 0.72 ALDH1A1 (0.51) ALDH1A1EGLN2GAANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2192841-A2 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AT LEAST ONE ADDITIONAL FUNGICIDE Basf Se (DE) 2010-06-09 EP claimed
WO-2009037242-A2 COMBINATIONS COMPRISING A FUNGICIDAL STRAIN AND AN ACTIVE COMPOUND BASF SE (DE) 2009-03-26 WO claimed
CN-106535633-B Composition containing lipochitooligosaccharides and microorganisms for enhancing plant growth 诺维信生物农业公司 2020-11-17 CN disclosed
EP-2180785-A2 USE OF HOMO- AND COPOLYMERS FOR STABILIZING ACTIVE INGREDIENT FORMULATIONS BASF SE (DE) 2010-05-05 EP disclosed
WO-2009007328-A2 USE OF HOMO- AND COPOLYMERS FOR STABILIZING ACTIVE INGREDIENT FORMULATIONS BASF SE (DE) 2009-01-15 WO disclosed