SCHEMBL3398583

SCHEMBL3398583

NNc1ccc2c3c(cccc13)C(=O)NC2=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.62
KMT2A Q03164 4/20 0.62
USP2 O75604 3/20 0.62
PARP1 P09874 3/20 0.62
MAPT P10636 3/20 0.62
POLB P06746 3/20 0.62
CYP1A2 P05177 2/20 0.62
NPSR1 Q6W5P4 2/20 0.62
CASP7 P55210 2/20 0.62
RGS12 O14924 1/20 0.62
CYP3A4 P08684 1/20 0.62
THRB P10828 1/20 0.62
CYP2C9 P11712 1/20 0.62
APEX1 P27695 1/20 0.62
CASP1 P29466 1/20 0.62
BRCA1 P38398 1/20 0.62
MTOR P42345 1/20 0.62
RECQL P46063 1/20 0.62
BLM P54132 1/20 0.62
GNAI1 P63096 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9081999 0.98 MEN1 (0.60) MEN1KMT2AUSP2PARP1MAPT
SCHEMBL25838097 0.87 BRD4 (0.56) MEN1KMT2AUSP2PARP1MAPT
SCHEMBL17529462 0.82 MEN1 (0.53) MEN1KMT2AUSP2PARP1MAPT
SCHEMBL2134658 0.81 TYMS (0.56) MEN1KMT2AUSP2PARP1MAPT
SCHEMBL6628883 0.80 PABPC1 (0.59) MEN1KMT2AUSP2PARP1MAPT
SCHEMBL9006308 0.79 MEN1 (0.58) MEN1KMT2AUSP2PARP1MAPT
SCHEMBL27649471 0.79 MEN1 (0.53) MEN1KMT2AUSP2PARP1MAPT
SCHEMBL8293068 0.78 KMT2A (0.54) MEN1KMT2AUSP2MAPTPOLB
SCHEMBL8062355 0.78 KDM4E (0.61) MEN1KMT2AUSP2PARP1MAPT
SCHEMBL5517131 0.77 MEN1 (0.51) MEN1KMT2AUSP2PARP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57145158-A None JP disclosed
CN-117925238-A Flexible quantum dot composite material and preparation method and application thereof 华南师范大学 2024-04-26 CN disclosed
CN-115745887-A Novel naphthylhydrazine, sugar naphthylhydrazone, synthesis method thereof and monosaccharide detection method 安徽中医药大学 2023-03-07 CN disclosed
CN-111073636-B Fluorescent probe for formaldehyde detection and preparation method and application thereof 南京师范大学 2023-01-31 CN disclosed
CN-111073636-A Fluorescent probe for formaldehyde detection and preparation method and application thereof 南京师范大学 2020-04-28 CN disclosed
CN-106478602-B A kind of colorimetric probe and the preparation method and application thereof based on naphthalimide derivative 河南理工大学 2018-10-16 CN disclosed
CN-106478602-A A kind of colorimetric probe based on naphthalimide derivative and preparation method and application 河南理工大学 2017-03-08 CN disclosed
CN-105542756-A Fluorescent probe for detecting formaldehyde as well as preparation method and application of fluorescent probe UNIV ZHEJIANG SCIENCE & TECH 2016-05-04 CN disclosed
EP-2251687-A1 Colorimetric anion sensor element The Provost Fellows And Scholars Of The College Of The Holy and Undivided Trinity Of Queen Elizabeth Near Dublin (IE) 2010-11-17 EP disclosed
CN-1150295-C Naphthoyl imine luminescence material to luminesce with red fluorescence 华东理工大学 2004-05-19 CN disclosed
CN-1324911-A Naphthoyl imine luminescence material to luminesce with red fluorescence UNIV EAST CHINA SCIENCE & ENG (CN) 2001-12-05 CN disclosed
EP-0647629-B1 Neurotensin active substituted 1-naphthylpyrazole-3-carboxamides, their preparation and pharmaceutical compositions containing them SANOFI SA (FR) 1999-07-07 EP disclosed
EP-0647629-A1 Neurotensin active substituted 1-naphthylpyrazole-3-carboxamides, their preparation and pharmaceutical compositions containing them SANOFI (FR) 1995-04-12 EP disclosed
JP-S57145158-A 4-(1-PYRENYL METHYLIDENE HYDRAZINO)-NAPHTHALIMIDE MITSUBISHI CHEM IND LTD 1982-09-08 JP disclosed