Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 2/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 4/20 | 0.55 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | USP2 | O75604 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28682214 | 0.83 | CYP1A2 (0.65) | PABPC1KEAP1NFE2L2CRHBPCRHR2 | |
| SCHEMBL2134658 | 0.81 | TYMS (0.56) | PABPC1KEAP1NFE2L2CRHBPCRHR2 | |
| SCHEMBL3398583 | 0.80 | MEN1 (0.62) | PABPC1KEAP1NFE2L2CYP1A2ALDH1A1 | |
| SCHEMBL28143359 | 0.79 | PABPC1 (0.59) | PABPC1KEAP1NFE2L2CRHBPCRHR2 | |
| SCHEMBL16200909 | 0.79 | MEN1 (0.64) | PABPC1KEAP1NFE2L2CRHBPCRHR2 | |
| SCHEMBL8293068 | 0.78 | KMT2A (0.54) | PABPC1KEAP1NFE2L2CYP1A2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9081999 | 0.78 | MEN1 (0.60) | PABPC1KEAP1NFE2L2CYP1A2ALDH1A1 | |
| SCHEMBL17740736 | 0.76 | MEN1 (0.61) | PABPC1KEAP1NFE2L2CRHBPCRHR2 | |
| SCHEMBL9283258 | 0.75 | PABPC1 (0.54) | PABPC1KEAP1NFE2L2CRHBPCRHR2 | |
| SCHEMBL3404873 | 0.73 | KMT2A (0.67) | KEAP1NFE2L2ALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894799-B1 | INDOLOMORPHINANE DERIVATIVES AND REMEDIES/PREVENTIVES FOR CEREBRAL DISORDERS | TORAY INDUSTRIES (JP) | 2004-04-07 | — | — | EP | disclosed |
| US-6156762-A | Indolomorphinan derivative and agent for curing and preventing cerebral disorder | TORAY INDUSTRIES, INC. (JP) | 2000-12-05 | — | — | US | disclosed |
| EP-0894799-A1 | INDOLOMORPHINANE DERIVATIVES AND REMEDIES/PREVENTIVES FOR CEREBRAL DISORDERS | TORAY INDUSTRIES, INC. (JP) | 1999-02-03 | — | — | EP | disclosed |