Known targets — ChEMBL curated mechanism
ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1HRH1HTR7IDH1IDH2IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.94 |
| ▸ | HMGCR | P04035 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SLC13A5 | Q86YT5 | 4/20 | 0.42 |
| ▸ | CPT2 | P23786 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL29740281 | 1.00 | ALDH1A1 (0.94) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL306676 | 1.00 | ALDH1A1 (0.94) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL3692334 | 1.00 | ALDH1A1 (0.94) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL524443 | 0.97 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL28961215 | 0.97 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL3793381 | 0.97 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL3792172 | 0.97 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL16345363 | 0.97 | ALDH1A1 (0.88) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL1331942 | 0.97 | ALDH1A1 (1.00) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| Citric Acid SCHEMBL10896997 | 0.97 | ALDH1A1 (1.00) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7285 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260146195-A1 | SINTERING POWDER | ALPHA ASSEMBLY SOLUTIONS INC. (US) | 2026-05-28 | — | — | US | claimed |
| CN-120311480-B | Polyamide 6 high-conductivity fabric for textile-based electronic products and preparation method thereof | QINGDAO UNIVERSITY (CN) | 2026-05-26 | — | — | CN | claimed |
| EP-4743053-A1 | ANTIMICROBIAL SYNERGIES | Symrise AG (DE) | 2026-05-20 | — | — | EP | claimed |
| WO-2026099171-A1 | ANTI-MICROBIAL COMPOSITION AND PREPARATION PROCESS AND USE THEREOF | CLARIANT INTERNATIONAL LTD (CH) | 2026-05-15 | — | — | WO | claimed |
| CN-122011838-A | Composite particle-free conductive ink and preparation method and application thereof | 丰宾电子科技股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122007402-A | Silver paste and silver sintered body | 丰田自动车株式会社 | 2026-05-12 | — | — | CN | claimed |
| CN-122004238-A | Antimicrobial compositions, methods of making and uses thereof | 科莱恩国际有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-12605477-B2 | Compositions and methods for decontamination of surfaces | Aviraban, LLC (US) | 2026-04-21 | — | — | US | claimed |
| US-12604898-B2 | Disilver hydrogen citrate-containing composition, method for producing same, antibacterial agent or antiviral agent using same, and method for producing same | SASAKI CHEMICAL INDUSTRY CO., LTD. (JP) | 2026-04-21 | — | — | US | claimed |
| EP-4169899-B1 | DISILVER HYDROGEN CITRATE-CONTAINING COMPOSITION, METHOD FOR PRODUCING SAME, ANTIBACTERIAL AGENT OR ANTIVIRAL AGENT USING SAME, AND METHOD FOR PRODUCING SAME | SASAKI CHEMICAL IND CO LTD (JP) | 2026-04-08 | — | — | EP | claimed |
| US-4299682-A | HAVING A POROUS LAYER MADE BY DECOMPOSING A GROUP EIGHT SALT OF A CARBOXYLIC ACID | ASAHI GLASS COMPANY, LTD. (JP) | 1981-11-10 | — | — | US | claimed |
| US-4229321-A | Process for making a silver catalyst | TEXACO DEVELOPMENT CORP. (US) | 1980-10-21 | — | — | US | claimed |
| US-4224194-A | CESIUM OR RUBIDIUM PROMOTED SILVER EPOXIDATION CATALYST | TEXACO DEVELOPMENT CORP. (US) | 1980-09-23 | — | — | US | claimed |
| EP-0014896-A1 | Gas diffusion electrode | ASAHI GLASS COMPANY LTD. (JP) | 1980-09-03 | — | — | EP | claimed |
| US-4206128-A | EPOXIDIZING ETHYLENE, SILVER CATALYST | TEXACO DEVELOPMENT CORPORATION (US) | 1980-06-03 | — | — | US | claimed |
| US-4121938-A | Photographic material containing TiO2, soluble Cu(II) salt, and soluble silver salt and the use thereof in physical development | FUJI PHOTO FILM CO., LTD. (JP) | 1978-10-24 | — | — | US | claimed |
| US-4097414-A | METALLIC SILVER, CESIUM PROMOTER, INORGANIC SUPPORT | TEXACO DEVELOPMENT CORP. (US) | 1978-06-27 | — | — | US | claimed |
| US-3990833-A | Switching devices for photoflash unit | GENERAL ELECTRIC COMPANY (US) | 1976-11-09 | — | — | US | claimed |
| US-3981916-A | Reduction of nitroparaffin substrates to their corresponding oximes using a silver salt catalyst | TEXACO INC. (US) | 1976-09-21 | — | — | US | claimed |
| US-3964255-A | Method of inflating an automobile passenger restraint bag | SPECIALTY PRODUCTS DEVELOPMENT CORPORATION (US) | 1976-06-22 | — | — | US | claimed |