Propionic Acid

Propionic Acid

SCHEMBL3398726

CC(C)C(=O)O.CCC(=O)O.CCC(O)CCO

nearest known ligand 0.40

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.40
THRB P10828 1/20 0.36
GABRP O00591 2/20 0.34
GABRD O14764 2/20 0.34
GABRA1 P14867 2/20 0.34
GABRB1 P18505 2/20 0.34
GABRG2 P18507 2/20 0.34
GABRB3 P28472 2/20 0.34
GABRA5 P31644 2/20 0.34
GABRA3 P34903 2/20 0.34
GABRA2 P47869 2/20 0.34
GABRB2 P47870 2/20 0.34
GABRA4 P48169 2/20 0.34
GABRE P78334 2/20 0.34
GABRA6 Q16445 2/20 0.34
GABRG1 Q8N1C3 2/20 0.34
GABRG3 Q99928 2/20 0.34
GABRQ Q9UN88 2/20 0.34
CYP1A2 P05177 1/20 0.34
GPR84 Q9NQS5 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1478232 0.94 THRB (0.40) THRBGABRPGABRDGABRA1GABRB1
SCHEMBL6229980 0.94 THRB (0.40) THRBGABRPGABRDGABRA1GABRB1
Propionic Acid SCHEMBL1071197 0.92 FFAR3 (0.48) FFAR3THRBGABRPGABRDGABRA1
Trimethylammonium SCHEMBL27654119 0.88 THRB (0.36) THRBGABRPGABRDGABRA1GABRB1
Trimethylammonium SCHEMBL27534380 0.88 THRB (0.36) THRBGABRPGABRDGABRA1GABRB1
Trimethylammonium SCHEMBL27546789 0.88 THRB (0.36) THRBGABRPGABRDGABRA1GABRB1
Bicarbonate SCHEMBL587478 0.83 THRB (0.46) THRBGABRPGABRDGABRA1GABRB1
Propionic Acid SCHEMBL3820518 0.79 THRB (0.62) FFAR3THRBGABRPGABRDGABRA1
Benzoic Acid SCHEMBL9853337 0.78 DAO (0.44) MAPK1
Butyric Acid SCHEMBL10558111 0.78 FFAR3 (0.54) FFAR3THRBGABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2246340-A1 Preparation of 2,5-furandialdehyde from 2,5-(hydroxymethyl)furanaldehyde in the presence of 2,2,6,6-tetramethyl-i-piperidinyloxyl ARCHER-DANIELS-MIDLAND COMPANY (US) 2010-11-03 EP disclosed
EP-2090573-A1 Conversion of 2,5-(hydroxymethyl) furaldehyde to 2,5-bis(hydroxymethyl)tetrahydofuran, purification of the derivatives and industrial uses therefor ARCHER-DANIELS-MIDLAND COMPANY (US) 2009-08-19 EP disclosed