Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 19/20 | 0.51 |
| ▸ | ESR1 | P03372 | 15/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1377599 | 0.83 | ESR2 (0.70) | ESR2ESR1HDAC6 | |
| SCHEMBL14266178 | 0.76 | ESR2 (0.52) | DHODHESR2ESR1HDAC6 | |
| SCHEMBL3400654 | 0.75 | ESR2 (0.70) | DHODHESR2ESR1HDAC6 | |
| SCHEMBL505539 | 0.72 | DHODH (1.00) | DHODHESR2ESR1 | |
| SCHEMBL31737306 | 0.71 | DHODH (0.72) | DHODHESR2ESR1 | |
| SCHEMBL5226889 | 0.71 | CEPT1 (0.53) | DHODHESR2ESR1HDAC6 | |
| SCHEMBL2399908 | 0.71 | ESR2 (0.70) | ESR2ESR1HDAC6 | |
| SCHEMBL121400 | 0.71 | DHODH (0.94) | DHODHESR2ESR1 | |
| SCHEMBL3703337 | 0.70 | DHODH (0.62) | DHODHESR2ESR1HDAC6 | |
| SCHEMBL4147765 | 0.70 | NPC1 (0.55) | DHODHESR2ESR1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250180-A1 | PHOSPHATE DERIVATIVES OF SUBSTITUTED BENZOXAZOLES | Wyeth LLC (US) | 2010-11-17 | — | — | EP | claimed |
| WO-2009100335-A1 | PHOSPHATE DERIVATIVES OF SUBSTITUTED BENZOXAZOLES | WYETH (US) | 2009-08-13 | — | — | WO | claimed |