Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26639082 | 0.92 | CYP2D6 (0.45) | — | |
| SCHEMBL30638244 | 0.92 | CYP2D6 (0.45) | — | |
| SCHEMBL30648540 | 0.90 | — | — | |
| SCHEMBL26639069 | 0.90 | — | — | |
| SCHEMBL27663775 | 0.88 | OPRM1 (0.50) | MEN1KMT2ANPSR1 | |
| SCHEMBL26791524 | 0.86 | — | — | |
| SCHEMBL26659294 | 0.84 | OPRD1 (0.43) | — | |
| SCHEMBL30638226 | 0.84 | OPRD1 (0.43) | — | |
| SCHEMBL16980487 | 0.83 | — | — | |
| SCHEMBL630728 | 0.83 | MEN1 (0.47) | MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247600-A2 | BENZOXAZOLE CARBOXAMIDE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | Lead Therapeutics, Inc. (US) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009099736-A2 | BENZOXAZOLE CARBOXAMIDE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | LEAD THERAPEUTICS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |