Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL580196 | 1.00 | TRPA1 (0.40) | TRPA1MAPTLMNAPGRCYP3A4 | |
| SCHEMBL3385631 | 1.00 | TRPA1 (0.40) | TRPA1MAPTLMNAPGRCYP3A4 | |
| SCHEMBL3392105 | 1.00 | TRPA1 (0.40) | TRPA1MAPTLMNAPGRCYP3A4 | |
| SCHEMBL3390303 | 1.00 | TRPA1 (0.40) | TRPA1MAPTLMNAPGRCYP3A4 | |
| SCHEMBL3392881 | 1.00 | TRPA1 (0.40) | TRPA1MAPTLMNAPGRCYP3A4 | |
| SCHEMBL25223417 | 0.84 | TRPA1 (0.38) | TRPA1MAPTALOX15 | |
| SCHEMBL25222905 | 0.83 | LMNA (0.38) | MAPTLMNAPGRCYP3A4CYP2D6 | |
| SCHEMBL25217163 | 0.83 | LMNA (0.38) | MAPTLMNAPGRCYP3A4CYP2D6 | |
| SCHEMBL25271559 | 0.83 | LMNA (0.38) | MAPTLMNAPGRCYP3A4CYP2D6 | |
| SCHEMBL25274021 | 0.83 | TRPA1 (0.41) | TRPA1MAPTLMNAPDE3ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1839653-B1 | THERAPEUTIC AGENT FOR SENSORY DISORDERS | MEIJI DAIRIES CORP (JP) | 2010-06-09 | — | — | EP | claimed |