Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.60 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13426215 | 0.92 | KIF11 (0.62) | KIF11PDE1CSMN1; SMN2NPSR1MAPK1 | |
| SCHEMBL3398042 | 0.92 | KIF11 (0.62) | KIF11PDE1CSMN1; SMN2NPSR1MAPK1 | |
| SCHEMBL13425966 | 0.92 | KIF11 (0.62) | KIF11PDE1CSMN1; SMN2NPSR1MAPK1 | |
| SCHEMBL3398148 | 0.91 | PDE1C (0.57) | KIF11PDE1CSMN1; SMN2NPSR1MAPK1 | |
| SCHEMBL3394451 | 0.91 | KIF11 (0.64) | KIF11PDE1CSMN1; SMN2NPSR1MAPK1 | |
| SCHEMBL3432561 | 0.88 | PDE1C (0.58) | KIF11PDE1CSMN1; SMN2NPSR1MAPK1 | |
| SCHEMBL3397010 | 0.87 | KIF11 (0.76) | KIF11PDE1CSMN1; SMN2NPSR1MAPK1 | |
| SCHEMBL3398630 | 0.86 | PDE1C (0.52) | KIF11PDE1CSMN1; SMN2NPSR1MAPK1 | |
| SCHEMBL3394067 | 0.83 | PDE1C (0.59) | KIF11PDE1CSMN1; SMN2NPSR1MAPK1 | |
| SCHEMBL3398285 | 0.83 | PDE1C (0.59) | KIF11PDE1CSMN1; SMN2NPSR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |