Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.54 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | GCGR | P47871 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL772274 | 0.83 | NISCH (0.58) | KIF11NISCHMTORADKCYP3A4 | |
| SCHEMBL378124 | 0.83 | NISCH (0.58) | KCNH2NISCHMTORADKCYP3A4 | |
| Hydrochloric Acid SCHEMBL29165675 | 0.81 | NISCH (0.56) | KCNH2NISCHMTORADKCYP3A4 | |
| SCHEMBL771236 | 0.78 | NISCH (0.64) | KCNH2GCGRMAPK14MAPK13MAPK12 | |
| Hydrochloric Acid SCHEMBL28346045 | 0.76 | NISCH (0.62) | KCNH2GCGRMAPK14MAPK13MAPK12 | |
| Bromide SCHEMBL28348957 | 0.76 | NISCH (0.62) | KCNH2GCGRMAPK14MAPK13MAPK12 | |
| SCHEMBL1507855 | 0.75 | KIF11 (0.47) | KIF11DGAT1SOAT1KCNH2CYP3A4 | |
| SCHEMBL13063632 | 0.73 | KIF11 (1.00) | KIF11DGAT1SOAT1KCNH2CYP3A4 | |
| SCHEMBL3456838 | 0.73 | KIF11 (1.00) | KIF11DGAT1SOAT1KCNH2CYP3A4 | |
| SCHEMBL29160561 | 0.72 | NISCH (0.56) | KCNH2GCGRMAPK14MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247603-A1 | PESTICIDAL COMPOSITIONS | Dow AgroSciences LLC (US) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009102736-A1 | PESTICIDAL COMPOSITIONS | DOW AGROSCIENCES LLC (US) | 2009-08-20 | — | — | WO | disclosed |