Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3397751 | 0.92 | MTNR1B (1.00) | MTNR1BMTNR1A | |
| SCHEMBL3399533 | 0.87 | MTNR1B (1.00) | MTNR1BMTNR1A | |
| SCHEMBL3394369 | 0.84 | MTNR1B (1.00) | MTNR1BMTNR1A | |
| SCHEMBL3398990 | 0.83 | MTNR1A (0.88) | MTNR1BMTNR1A | |
| SCHEMBL3396891 | 0.83 | MTNR1B (1.00) | MTNR1BMTNR1A | |
| SCHEMBL30080381 | 0.82 | MTNR1B (0.88) | MTNR1BMTNR1A | |
| SCHEMBL3396116 | 0.81 | MTNR1A (0.91) | MTNR1BMTNR1A | |
| SCHEMBL1133198 | 0.81 | MTNR1A (0.68) | MTNR1BMTNR1A | |
| SCHEMBL3397360 | 0.80 | MTNR1B (1.00) | MTNR1BMTNR1A | |
| SCHEMBL30080273 | 0.80 | MTNR1B (0.83) | MTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160221932-A1 | Methods and Uses of Melatonin Ligands | DOMINGUEZ LOPEZ SERGIO (US) | 2016-08-04 | — | — | US | claimed |
| EP-1973868-B1 | Novel elatonin ligands having antidepressant activity as well as sleep inducing properties | UNIV MCGILL (CA) | 2015-09-09 | — | — | EP | claimed |
| WO-2015021535-A1 | METHODS AND USES OF MELATONIN LIGANDS | GOBBI GABRIELLA (CA) | 2015-02-19 | — | — | WO | claimed |
| US-20150045442-A1 | NOVEL MELATONIN LIGANDS HAVING ANTIDEPRESSANT ACTIVITY AS WELL AS SLEEP INDUCING PROPERTIES | GOBBI GABRIELLA (CA) | 2015-02-12 | — | — | US | claimed |
| US-20100267836-A1 | NOVEL MELATONIN LIGANDS HAVING ANTIDEPRESSANT ACTIVITY AS WELL AS SLEEP INDUCING PROPERTIES | UNIVERSITA DEGLI STUDI DI MILANO (IT) | 2010-10-21 | — | — | US | claimed |
| US-20160221932-A1 | Methods and Uses of Melatonin Ligands | DOMINGUEZ LOPEZ SERGIO (US) | 2016-08-04 | — | — | US | disclosed |
| EP-1973868-B1 | Novel elatonin ligands having antidepressant activity as well as sleep inducing properties | UNIV MCGILL (CA) | 2015-09-09 | — | — | EP | disclosed |
| WO-2015021535-A1 | METHODS AND USES OF MELATONIN LIGANDS | GOBBI GABRIELLA (CA) | 2015-02-19 | — | — | WO | disclosed |
| US-20150045442-A1 | NOVEL MELATONIN LIGANDS HAVING ANTIDEPRESSANT ACTIVITY AS WELL AS SLEEP INDUCING PROPERTIES | GOBBI GABRIELLA (CA) | 2015-02-12 | — | — | US | disclosed |
| US-8791163-B2 | Melatonin ligands having antidepressant activity as well as sleep inducing properties | MCGILL UNIVERSITY (CA) | 2014-07-29 | — | — | US | disclosed |
| US-8303821-B2 | Reduction of antimicrobial compound levels during product dispensing | ROHM AND HAAS COMPANY (US) | 2012-11-06 | — | — | US | disclosed |
| US-20100270241-A1 | REDUCTION OF ANTIMICROBIAL COMPOUND LEVELS DURING PRODUCT DISPENSING | ROHM AND HAAS COMPANY | 2010-10-28 | — | — | US | disclosed |
| US-20100267836-A1 | NOVEL MELATONIN LIGANDS HAVING ANTIDEPRESSANT ACTIVITY AS WELL AS SLEEP INDUCING PROPERTIES | UNIVERSITA DEGLI STUDI DI MILANO (IT) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160221932-A1 | Methods and Uses of Melatonin Ligands | MTNR1A, MTNR1B, MC3R | MTNR1B 2/4885MTNR1A 1/4885 |
| US-20100267836-A1 | NOVEL MELATONIN LIGANDS HAVING ANTIDEPRESSANT ACTIVITY AS WELL AS SLEEP INDUCING PROPERTIES | HCRTR1, HCRTR2, MTNR1A | MTNR1B 5/4885MTNR1A 3/4885 |
| US-20150045442-A1 | NOVEL MELATONIN LIGANDS HAVING ANTIDEPRESSANT ACTIVITY AS WELL AS SLEEP INDUCING PROPERTIES | HCRTR1, HCRTR2, MTNR1A | MTNR1B 5/4885MTNR1A 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.