Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.63 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.58 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.57 |
| ▸ | TNKS | O95271 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | GABRP | O00591 | 3/20 | 0.51 |
| ▸ | GABRD | O14764 | 3/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.51 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.51 |
| ▸ | GABRE | P78334 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803387 | 1.00 | PPARG (0.63) | PPARGCYP11B1CYP11B2SIGMAR1TNKS | |
| SCHEMBL12324682 | 0.85 | PPARG (0.63) | PPARGCYP11B1CYP11B2SIGMAR1TNKS | |
| SCHEMBL3715533 | 0.82 | PPARG (0.69) | PPARGCYP11B1CYP11B2SIGMAR1TNKS | |
| SCHEMBL30694898 | 0.82 | PPARG (0.69) | PPARGCYP11B1CYP11B2SIGMAR1TNKS | |
| SCHEMBL30876965 | 0.81 | PPARG (0.63) | PPARGCYP11B1CYP11B2SIGMAR1TNKS | |
| SCHEMBL3814678 | 0.81 | PPARG (0.63) | PPARGCYP11B1CYP11B2SIGMAR1TNKS | |
| SCHEMBL3395103 | 0.81 | PPARG (0.63) | PPARGCYP11B1CYP11B2SIGMAR1TNKS | |
| SCHEMBL5695477 | 0.81 | PPARG (0.63) | PPARGCYP11B1CYP11B2SIGMAR1TNKS | |
| SCHEMBL9972758 | 0.81 | PPARG (0.63) | PPARGCYP11B1CYP11B2SIGMAR1TNKS | |
| SCHEMBL9471231 | 0.81 | PPARG (0.63) | PPARGCYP11B1CYP11B2SIGMAR1TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4090654-B1 | METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS | LUPIN LTD (IN) | 2025-07-09 | — | — | EP | claimed |
| US-12344592-B2 | Methods, processes and intermediates for preparing chroman compounds | LUPIN LIMITED (IN) | 2025-07-01 | — | — | US | claimed |
| CN-114981253-B | Process and intermediates for preparing chroman compounds and methods therefor | 印度鲁宾有限公司 | 2024-06-18 | — | — | CN | claimed |
| US-20230140054-A1 | METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS | LUPIN LIMITED (IN) | 2023-05-04 | — | — | US | claimed |
| EP-4090654-A1 | METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS | Lupin Limited (IN) | 2022-11-23 | — | — | EP | claimed |
| CN-114981253-A | Process and intermediates for preparing chroman compounds and methods therefor | 印度鲁宾有限公司 | 2022-08-30 | — | — | CN | claimed |
| WO-2021144814-A1 | METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS | LUPIN LIMITED (IN) | 2021-07-22 | — | — | WO | claimed |
| EP-3253750-B1 | NOVEL FLAVONE BASED EGFR INHIBITORS AND PROCESS FOR PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2019-04-10 | — | — | EP | claimed |
| EP-4090654-B1 | METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS | LUPIN LTD (IN) | 2025-07-09 | — | — | EP | disclosed |
| US-12344592-B2 | Methods, processes and intermediates for preparing chroman compounds | LUPIN LIMITED (IN) | 2025-07-01 | — | — | US | disclosed |
| CN-114981253-B | Process and intermediates for preparing chroman compounds and methods therefor | 印度鲁宾有限公司 | 2024-06-18 | — | — | CN | disclosed |
| US-20230140054-A1 | METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS | LUPIN LIMITED (IN) | 2023-05-04 | — | — | US | disclosed |
| US-20230140054-A1 | METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS | LUPIN LIMITED (IN) | 2023-05-04 | — | — | US | disclosed |
| US-20230140054-A1 | METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS | LUPIN LIMITED (IN) | 2023-05-04 | — | — | US | disclosed |
| EP-0632035-A1 | Aminoalkylchomones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-01-04 | — | — | EP | disclosed |
| EP-0580503-A1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-01-26 | — | — | EP | disclosed |
| US-5082849-A | Antiinflammatory agents or antiallergens | AVENTIS PHARMACEUTICALS INC. | 1992-01-21 | — | — | US | disclosed |
| EP-0434827-A1 | QUINOLINYL-BENZOPYRAN DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D 4? | RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1991-07-03 | — | — | EP | disclosed |
| WO-1991001123-A2 | QUINOLINYL-BENZOPYRAN DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1991-02-07 | — | — | WO | disclosed |
| US-4977162-A | Quinolinyl-chromone derivatives and use for treatment of hypersensitive ailments | RORER PHARMACEUTICAL CORPORATION (US) | 1990-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230140054-A1 | METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS | CASR, CALCR, RYR1 | PPARG 824/4885CYP11B1 571/4885CYP11B2 686/4885 |
| US-12344592-B2 | Methods, processes and intermediates for preparing chroman compounds | CASR, CALCR, RYR1 | PPARG 824/4885CYP11B1 571/4885CYP11B2 686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.