SCHEMBL3395103

SCHEMBL3395103

O=c1cc(CO)oc2ccccc12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.63
CYP11B1 P15538 2/20 0.58
CYP11B2 P19099 2/20 0.58
KDM4E B2RXH2 5/20 0.54
USP2 O75604 1/20 0.54
CSNK2A2 P19784 1/20 0.54
PTGS1 P23219 1/20 0.54
CSNK2B P67870 1/20 0.54
CSNK2A1 P68400 1/20 0.54
CSNK2A3 Q8NEV1 1/20 0.54
SIGMAR1 Q99720 2/20 0.54
SMN1; SMN2 Q16637 4/20 0.51
NPC1 O15118 4/20 0.51
TNKS O95271 4/20 0.51
HPGD P15428 4/20 0.51
RAB9A P51151 3/20 0.51
CYP3A4 P08684 3/20 0.51
PARP1 P09874 3/20 0.51
TNKS2 Q9H2K2 3/20 0.51
PLA2G2A P14555 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29802950 1.00 PPARG (0.63) PPARGCYP11B1CYP11B2KDM4EUSP2
SCHEMBL19925815 0.86 PPARG (0.69) PPARGCYP11B1CYP11B2KDM4EUSP2
SCHEMBL5695477 0.81 PPARG (0.63) PPARGCYP11B1CYP11B2KDM4EUSP2
SCHEMBL9471231 0.81 PPARG (0.63) PPARGCYP11B1CYP11B2KDM4EUSP2
SCHEMBL29803387 0.81 PPARG (0.63) PPARGCYP11B1CYP11B2KDM4EUSP2
SCHEMBL9972758 0.81 PPARG (0.63) PPARGCYP11B1CYP11B2KDM4EUSP2
SCHEMBL3814678 0.81 PPARG (0.63) PPARGCYP11B1CYP11B2KDM4EUSP2
SCHEMBL30876965 0.81 PPARG (0.63) PPARGCYP11B1CYP11B2KDM4EUSP2
SCHEMBL3399447 0.81 PPARG (0.63) PPARGCYP11B1CYP11B2KDM4EUSP2
SCHEMBL11637530 0.81 PPARG (0.63) PPARGCYP11B1CYP11B2KDM4EUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4090654-B1 METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS LUPIN LTD (IN) 2025-07-09 EP claimed
US-12344592-B2 Methods, processes and intermediates for preparing chroman compounds LUPIN LIMITED (IN) 2025-07-01 US claimed
CN-114981253-B Process and intermediates for preparing chroman compounds and methods therefor 印度鲁宾有限公司 2024-06-18 CN claimed
US-20230140054-A1 METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS LUPIN LIMITED (IN) 2023-05-04 US claimed
EP-4090654-A1 METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS Lupin Limited (IN) 2022-11-23 EP claimed
CN-114981253-A Process and intermediates for preparing chroman compounds and methods therefor 印度鲁宾有限公司 2022-08-30 CN claimed
WO-2021144814-A1 METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS LUPIN LIMITED (IN) 2021-07-22 WO claimed
US-12390444-B2 Stabilizing vitamin C topical formulations MF BEAUTY PARTNERS LLC (US) 2025-08-19 US disclosed
US-20250228756-A1 Anhydrous Urea Emulsions with a Retinoid Agent MF BEAUTY PARTNERS LLC 2025-07-17 US disclosed
EP-4090654-B1 METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS LUPIN LTD (IN) 2025-07-09 EP disclosed
US-12344592-B2 Methods, processes and intermediates for preparing chroman compounds LUPIN LIMITED (IN) 2025-07-01 US disclosed
US-20250114288-A1 HIGH-POTENCY VITAMIN C AND SUGAR ALCOHOL TOPICAL FORMULATIONS MF BEAUTY PARTNERS LLC 2025-04-10 US disclosed
US-20240390238-A1 MINIMALIST EMULSION COMPOSITIONS ICB (an ABC), LLC 2024-11-28 US disclosed
US-8349850-B2 Heterocyclic compounds and uses thereof in the treatment of sexual disorders ATIR HOLDING S.A. (LU) 2013-01-08 US disclosed
EP-2233472-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF IN THE TREATMENT OF SEXUAL DISORDERS Atir Holding S.A. (LU) 2010-09-29 EP disclosed
US-20100029671-A1 Heterocyclic Compounds And Uses Thereof In The Treatment Of Sexual Disorders ATIR HOLDING S.A. (LU) 2010-02-04 US disclosed
EP-2010505-A2 HETEROCYCLIC COMPOUNDS AND USES THEREOF IN THE TREATMENT OF SEXUAL DISORDERS Atir Holding S.A. (LU) 2009-01-07 EP disclosed
WO-2007110868-A2 HETEROCYCLIC COMPOUNDS AND USES THEREOF IN THE TREATMENT OF SEXUAL DISORDERS ATIR HOLDING S.A. (LU) 2007-10-04 WO disclosed
US-4179447-A ANTIALLERGENS WARNER-LAMBERT COMPANY (US) 1979-12-18 US disclosed
US-4158663-A FROM 4-METHOXYCOUMARINS USING SODIUM HYDRIDE AND DIMETHYLSULFOXIDE WARNER-LAMBERT COMPANY (US) 1979-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100029671-A1 Heterocyclic Compounds And Uses Thereof In The Treatment Of Sexual Disorders PDE5A, PDE3B, PDE3A PPARG 722/4885CYP11B1 112/4885CYP11B2 100/4885
US-20230140054-A1 METHODS, PROCESSES AND INTERMEDIATES FOR PREPARING CHROMAN COMPOUNDS CASR, CALCR, RYR1 PPARG 824/4885CYP11B1 571/4885CYP11B2 686/4885
US-20250114288-A1 HIGH-POTENCY VITAMIN C AND SUGAR ALCOHOL TOPICAL FORMULATIONS PROC, ADH1C, GALC PPARG 1877/4885CYP11B1 3811/4885CYP11B2 3922/4885
US-20240390238-A1 MINIMALIST EMULSION COMPOSITIONS ADH7, PROC, OTC PPARG 546/4885CYP11B1 3426/4885CYP11B2 3240/4885
US-12390444-B2 Stabilizing vitamin C topical formulations PROC, CUTA, NISCH PPARG 1829/4885CYP11B1 4051/4885CYP11B2 4195/4885
US-12344592-B2 Methods, processes and intermediates for preparing chroman compounds CASR, CALCR, RYR1 PPARG 824/4885CYP11B1 571/4885CYP11B2 686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.