Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 6/20 | 1.00 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.78 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366045 | 0.88 | OXTR (1.00) | OXTRAVPR1AMAPTALDH1A1HPGD | |
| SCHEMBL3366047 | 0.88 | OXTR (1.00) | OXTRAVPR1AMAPTALDH1A1HPGD | |
| SCHEMBL3366536 | 0.85 | OXTR (0.74) | OXTRAVPR1AMAPTALDH1A1HPGD | |
| SCHEMBL3369096 | 0.85 | OXTR (0.74) | OXTRAVPR1AMAPTALDH1A1HPGD | |
| SCHEMBL3367779 | 0.83 | OXTR (0.71) | OXTRAVPR1AMAPTALDH1A1HPGD | |
| SCHEMBL3365017 | 0.82 | OXTR (0.85) | OXTRAVPR1AMAPTALDH1A1HPGD | |
| SCHEMBL3365010 | 0.82 | OXTR (0.85) | OXTRAVPR1AMAPTALDH1A1HPGD | |
| SCHEMBL14349092 | 0.80 | OXTR (0.87) | OXTRAVPR1AMAPTALDH1A1HPGD | |
| SCHEMBL3366825 | 0.79 | OXTR (1.00) | OXTRAVPR1AMAPTALDH1A1KMT2A | |
| SCHEMBL3366818 | 0.79 | OXTR (1.00) | OXTRAVPR1AMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335901-B1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | MERCK SERONO SA (CH) | 2010-04-14 | — | — | EP | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |