Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 6/20 | 0.71 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399452 | 0.83 | OXTR (1.00) | OXTRAVPR1AKMT2AMEN1POLB | |
| SCHEMBL5643236 | 0.80 | MAPT (0.62) | KMT2AMEN1POLBATMMAPT | |
| SCHEMBL5643240 | 0.80 | MAPT (0.62) | KMT2AMEN1POLBATMMAPT | |
| SCHEMBL21647692 | 0.76 | SMN1; SMN2 (0.60) | OXTRAVPR1AKMT2AMEN1MAPT | |
| SCHEMBL3365010 | 0.76 | OXTR (0.85) | OXTRAVPR1AKMT2AMEN1POLB | |
| SCHEMBL3365017 | 0.76 | OXTR (0.85) | OXTRAVPR1AKMT2AMEN1POLB | |
| SCHEMBL3367782 | 0.73 | SMN1; SMN2 (0.51) | OXTRAVPR1AMAPTALDH1A1HPGD | |
| SCHEMBL3367773 | 0.73 | OXTR (1.00) | OXTRAVPR1AKMT2AMEN1POLB | |
| SCHEMBL3366825 | 0.73 | OXTR (1.00) | OXTRAVPR1AKMT2AMEN1POLB | |
| SCHEMBL3366818 | 0.73 | OXTR (1.00) | OXTRAVPR1AKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335901-B1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | MERCK SERONO SA (CH) | 2010-04-14 | — | — | EP | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |