⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL927433 | 0.84 | LMNA (0.31) | — | |
| SCHEMBL927504 | 0.79 | TSHR (0.32) | — | |
| SCHEMBL7759589 | 0.78 | TAAR1 (0.38) | — | |
| SCHEMBL927622 | 0.75 | LMNA (0.31) | — | |
| SCHEMBL5607146 | 0.74 | TDP1 (0.42) | — | |
| SCHEMBL3400151 | 0.72 | TSHR (0.33) | — | |
| SCHEMBL928235 | 0.72 | NPC1 (0.33) | — | |
| SCHEMBL927434 | 0.70 | TSHR (0.33) | — | |
| SCHEMBL928560 | 0.70 | HDAC4 (0.34) | — | |
| SCHEMBL929186 | 0.69 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121349-B1 | RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2010-11-17 | — | — | EP | disclosed |
| US-7625965-B2 | Rubber composition, process of preparing same and articles made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-12-01 | — | — | US | disclosed |
| EP-2121349-A1 | RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM | Momentive Performance Materials Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008097587-A1 | RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC (US) | 2008-08-14 | — | — | WO | disclosed |
| US-20080194746-A1 | Rubber composition, process of preparing same and articles made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-08-14 | — | — | US | disclosed |