Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL574403 | 0.90 | ESR1 (0.33) | TDP1 | |
| SCHEMBL926681 | 0.89 | TSHR (0.33) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL927433 | 0.85 | LMNA (0.31) | TDP1 | |
| SCHEMBL27135638 | 0.84 | PTGS2 (0.36) | TDP1 | |
| SCHEMBL926509 | 0.84 | PGK1 (0.31) | — | |
| SCHEMBL3397079 | 0.82 | CHRNA7 (0.34) | TDP1 | |
| SCHEMBL28418566 | 0.82 | ESR1 (0.47) | TSHRTDP1 | |
| SCHEMBL926983 | 0.82 | SMN1; SMN2 (0.34) | MAPK1L3MBTL1 | |
| SCHEMBL926926 | 0.81 | TSHR (0.32) | TSHRMAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL928450 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207782-A2 | HALO-FUNCTIONAL SILANE, PROCESS FOR ITS PREPARATION, RUBBER COMPOSITION CONTAINING SAME AND ARTICLES MANUFACTURED THEREFROM | Momentive Performance Materials Inc. (US) | 2010-07-21 | — | — | EP | claimed |
| US-7625965-B2 | Rubber composition, process of preparing same and articles made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-12-01 | — | — | US | claimed |
| EP-2121349-A1 | RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM | Momentive Performance Materials Inc. (US) | 2009-11-25 | — | — | EP | claimed |
| WO-2009058373-A2 | HALO-FUNCTIONAL SILANE, PROCESS FOR ITS PREPARATION, RUBBER COMPOSITION CONTAINING SAME AND ARTICLES MANUFACTURED THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-05-07 | — | — | WO | claimed |
| US-20090111923-A1 | Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. | 2009-04-30 | — | — | US | claimed |
| WO-2008097587-A1 | RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC (US) | 2008-08-14 | — | — | WO | claimed |
| US-20080194746-A1 | Rubber composition, process of preparing same and articles made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-08-14 | — | — | US | claimed |
| EP-2708546-B1 | Halo-Functional Silane, process for its preparation, rubber composition containing same and articles manufactured therefrom | MOMENTIVE PERFORMANCE MAT INC (US) | 2016-01-06 | — | — | EP | disclosed |
| EP-2708546-A1 | Halo-Functional Silane, process for its preparation, rubber composition containing same and articles manufactured therefrom | Momentive Performance Materials Inc. (US) | 2014-03-19 | — | — | EP | disclosed |
| EP-2207782-B1 | HALO-FUNCTIONAL SILANE, PROCESS FOR ITS PREPARATION, RUBBER COMPOSITION CONTAINING SAME AND ARTICLES MANUFACTURED THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2014-02-26 | — | — | EP | disclosed |
| US-8372906-B2 | Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2013-02-12 | — | — | US | disclosed |
| US-20110003922-A1 | Halo-Functional Silane, Process For Its Preparation, Rubber Composition Containing Same and Articles Manufactured Therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-01-06 | — | — | US | disclosed |
| EP-2121349-B1 | RUBBER COMPOSITION, PROCESS OF PREPARING SAME AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MAT INC (US) | 2010-11-17 | — | — | EP | disclosed |
| US-7816435-B2 | Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2010-10-19 | — | — | US | disclosed |
| EP-2207782-A2 | HALO-FUNCTIONAL SILANE, PROCESS FOR ITS PREPARATION, RUBBER COMPOSITION CONTAINING SAME AND ARTICLES MANUFACTURED THEREFROM | Momentive Performance Materials Inc. (US) | 2010-07-21 | — | — | EP | disclosed |
| US-7625965-B2 | Rubber composition, process of preparing same and articles made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-12-01 | — | — | US | disclosed |
| WO-2009058373-A2 | HALO-FUNCTIONAL SILANE, PROCESS FOR ITS PREPARATION, RUBBER COMPOSITION CONTAINING SAME AND ARTICLES MANUFACTURED THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-05-07 | — | — | WO | disclosed |
| US-20090111923-A1 | Halo-functional silane, process for its preparation, rubber composition containing same and articles manufactured therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. | 2009-04-30 | — | — | US | disclosed |
| US-20080194746-A1 | Rubber composition, process of preparing same and articles made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. | 2008-08-14 | — | — | US | disclosed |