Melevodopa

Melevodopa

SCHEMBL34004

COC(=O)[C@@H](N)Cc1ccc(O)c(O)c1

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 6/20 0.66
KDM4E B2RXH2 4/20 0.66
HIF1A Q16665 4/20 0.66
HSD17B10 Q99714 4/20 0.66
RECQL P46063 3/20 0.66
SLC7A5 Q01650 3/20 0.66
LCK P06239 2/20 0.66
USP2 O75604 2/20 0.66
ADORA3 P0DMS8 2/20 0.66
HTR2A P28223 2/20 0.66
PTGS2 P35354 2/20 0.66
TDP1 Q9NUW8 2/20 0.66
PTGS1 P23219 2/20 0.66
EGFR P00533 1/20 0.66
FYN P06241 1/20 0.66
ALDH1A1 P00352 4/20 0.54
MMP1 P03956 1/20 0.52
MMP2 P08253 1/20 0.52
MMP3 P08254 1/20 0.52
MMP9 P14780 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Melevodopa SCHEMBL167562 1.00 ALOX15 (0.66) ALOX15KDM4EHIF1AHSD17B10RECQL
Melevodopa SCHEMBL27888379 1.00 ALOX15 (0.66) ALOX15KDM4EHIF1AHSD17B10RECQL
Melevodopa SCHEMBL30064486 1.00 ALOX15 (0.66) ALOX15KDM4EHIF1AHSD17B10RECQL
Melevodopa SCHEMBL29350486 1.00 ALOX15 (0.66) ALOX15KDM4EHIF1AHSD17B10RECQL
Melevodopa SCHEMBL8470037 1.00 ALOX15 (0.66) ALOX15KDM4EHIF1AHSD17B10RECQL
Melevodopa SCHEMBL1149493 0.98 ALOX15 (0.64) ALOX15KDM4EHIF1AHSD17B10RECQL
Melevodopa SCHEMBL29406901 0.98 ALOX15 (0.64) ALOX15KDM4EHIF1AHSD17B10RECQL
Melevodopa SCHEMBL453411 0.98 ALOX15 (0.64) ALOX15KDM4EHIF1AHSD17B10RECQL
Melevodopa SCHEMBL28836862 0.98 ALOX15 (0.64) ALOX15KDM4EHIF1AHSD17B10RECQL
Melevodopa SCHEMBL17747950 0.98 ALOX15 (0.64) ALOX15KDM4EHIF1AHSD17B10RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 23254 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026100654-A1 NUCLEIC ACID INTRODUCTION AID, NUCLEIC ACID INTRODUCTION AGENT, AND NUCLEIC ACID INTRODUCTION METHOD 株式会社インファーマシア 2026-05-15 WO claimed
EP-4736841-A1 A MUCOADHESIVE LAYER FOR BUCCAL ADMINISTRATION OF AN ACTIVE PHARMACEUTICAL INGREDIENT IQ medical GmbH (DE) 2026-05-06 EP claimed
US-12605345-B2 Transdermal drug delivery system BioPhysics Pharma, Inc. (US) 2026-04-21 US claimed
EP-4717276-A2 OPHTHALMIC COMPOSITIONS COMPRISING LEVODOPA, AN ANTIOXIDANT AND AN AQUEOUS CARRIER University of Canberra (AU) 2026-04-01 EP claimed
EP-4704826-A1 COMPOSITIONS AND METHODS FOR TREATING POST-TRAUMATIC STRESS DISORDER Yale University (US) 2026-03-11 EP claimed
EP-4704839-A2 IMIDAZOLE CONTAINING COMPOUNDS, DERIVATIVES THEREFORE, AND USES THEREOF ALPHERABIO LLC (US) 2026-03-11 EP claimed
US-12564596-B2 Agents and methods for modulating pathogen activity GRIFFITH UNIVERSITY (AU) 2026-03-03 US claimed
US-20260027178-A1 Treatment Of Parkinson's Disease With SIM BHLH Transcription Factor 2 (SIM2) Agonists REGENERON PHARMA (US) 2026-01-29 US claimed
US-12533417-B2 L-DOPA and/or DOPA decarboxylse inhibitors conjugated to sugar for the treatment of dopamine-responsive disorders B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY (IL) 2026-01-27 US claimed
US-12521398-B2 Composition for treating synucleinopathies STANDIGM INC. (KR) 2026-01-13 US claimed
US-4315033-A Method of treating menopausal symptoms LAWRASON F DOUGLAS 1982-02-09 US claimed
US-4313956-A Novel sypathomimetic amine prodrugs INTERX RESEARCH CORP. (US) 1982-02-02 US claimed
EP-0036145-A1 An orally administered drug form comprising a polar bioactive agent and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-23 EP claimed
EP-0031561-A2 A rectally administered suppository comprising a drug and an adjuvant MERCK & CO. INC. (US) 1981-07-08 EP claimed
US-4256108-A Microporous-semipermeable laminated osmotic system ALZA CORPORATION (US) 1981-03-17 US claimed
US-4247550-A Compositions and methods for the treatment of hypertension or oedemas LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) 1981-01-27 US claimed
US-4241082-A 3,4-DIHYDROXYPHENYLALANINE OR DERIVATIVE THEREOF AS A DECARBOXYLASE INHIBITOR USED IN CONJUNCTION WITH AN AMINO ACID SANKYO COMPANY LIMITED (JP) 1980-12-23 US claimed
EP-0012401-A1 Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them MERCK & CO. INC. (US) 1980-06-25 EP claimed
EP-0011868-A1 Methyldopa composition MERCK & CO. INC. (US) 1980-06-11 EP claimed
US-3961041-A PARKINSON'S DISEASE INTERX RESEARCH CORPORATION (US) 1976-06-01 US claimed