Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.66 |
| ▸ | RECQL | P46063 | 3/20 | 0.66 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.66 |
| ▸ | LCK | P06239 | 2/20 | 0.66 |
| ▸ | USP2 | O75604 | 2/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.66 |
| ▸ | HTR2A | P28223 | 2/20 | 0.66 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.66 |
| ▸ | EGFR | P00533 | 1/20 | 0.66 |
| ▸ | FYN | P06241 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Melevodopa SCHEMBL27888379 | 1.00 | ALOX15 (0.66) | ALOX15KDM4EHIF1AHSD17B10RECQL | |
| Melevodopa SCHEMBL30064486 | 1.00 | ALOX15 (0.66) | ALOX15KDM4EHIF1AHSD17B10RECQL | |
| Melevodopa SCHEMBL29350486 | 1.00 | ALOX15 (0.66) | ALOX15KDM4EHIF1AHSD17B10RECQL | |
| Melevodopa SCHEMBL8470037 | 1.00 | ALOX15 (0.66) | ALOX15KDM4EHIF1AHSD17B10RECQL | |
| Melevodopa SCHEMBL34004 | 1.00 | ALOX15 (0.66) | ALOX15KDM4EHIF1AHSD17B10RECQL | |
| Melevodopa SCHEMBL1149493 | 0.98 | ALOX15 (0.64) | ALOX15KDM4EHIF1AHSD17B10RECQL | |
| Melevodopa SCHEMBL29406901 | 0.98 | ALOX15 (0.64) | ALOX15KDM4EHIF1AHSD17B10RECQL | |
| Melevodopa SCHEMBL453411 | 0.98 | ALOX15 (0.64) | ALOX15KDM4EHIF1AHSD17B10RECQL | |
| Melevodopa SCHEMBL28836862 | 0.98 | ALOX15 (0.64) | ALOX15KDM4EHIF1AHSD17B10RECQL | |
| Melevodopa SCHEMBL17747950 | 0.98 | ALOX15 (0.64) | ALOX15KDM4EHIF1AHSD17B10RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 467 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113789069-A | White carbon black dispersing auxiliary agent and preparation method and application thereof | 浦林成山（青岛）工业研究设计有限公司 | 2021-12-14 | — | — | CN | claimed |
| US-20210220523-A1 | NO RELEASING COATED PROSTHETIC VASCULAR GRAFTS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2021-07-22 | — | — | US | claimed |
| EP-3826628-A1 | NO RELEASING COATED PROSTHETIC VASCULAR GRAFTS | University of Georgia Research Foundation, Inc. (US) | 2021-06-02 | — | — | EP | claimed |
| WO-2020041617-A1 | NO RELEASING COATED PROSTHETIC VASCULAR GRAFTS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2020-02-27 | — | — | WO | claimed |
| CN-109689036-A | Pulsed drug delivery system for treatment of morning akinesia | 康特拉医药公司 | 2019-04-26 | — | — | CN | claimed |
| WO-2019038638-A1 | PROCESS FOR PREPARING PURIFIED LEVODOPA AMIDE | NEURODERM LTD (IL) | 2019-02-28 | — | — | WO | claimed |
| CN-105658211-A | Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof | 怡百克制药公司 | 2016-06-08 | — | — | CN | claimed |
| CN-103364512-A | Method for detecting concentration of levodopa methyl ester and levodopa in blood plasma | NANJING CHANGAO PHARMACEUTICAL SCIENCE AND TECHNOLOGY CO LTD | 2013-10-23 | — | — | CN | claimed |
| US-8541060-B2 | coating an alkaline solution comprising 3,4-dihydroxy-L-phenylalanine, dopamine, norepinephrine or epinephrine; coupling the metal, or proteins, or nucleic acids; silver metal layer formed on polydopamine-coated silicon nitride; anti-biofouling on medical device catheters, stents or semiconductor sensors | NORTHWESTERN UNIVERSITY (US) | 2013-09-24 | — | — | US | claimed |
| US-20110136704-A1 | Methods of Treating a Hydrocarbon-Bearing Formation, a Well Bore, and Particles | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2011-06-09 | — | — | US | claimed |
| JP-3556216-B2 | — | — | 2004-08-18 | — | — | JP | claimed |
| EP-0658093-B1 | PROCESS AND KIT FOR DYEING HAIR | BRISTOL MYERS SQUIBB CO (US) | 2000-06-07 | — | — | EP | claimed |
| CN-1050992-C | Method for dyeing hair and complete set of hair-dyestuff | BRISTOL MYERS SQUIBB CO LTD (US) | 2000-04-05 | — | — | CN | claimed |
| US-5750093-A | 33 Lipomelanin sunscreen composition | DUSA PHARMACEUTICALS, INC. (CA) | 1998-05-12 | — | — | US | claimed |
| US-5643554-A | Lipomelanim composition | DUSA PHARMACEUTICALS, INC. (CA) | 1997-07-01 | — | — | US | claimed |
| EP-0658093-A1 | PROCESS AND KIT FOR DYEING HAIR | Bristol-Myers Squibb Company (US) | 1995-06-21 | — | — | EP | claimed |
| EP-0658093-A4 | PROCESS AND KIT FOR DYEING HAIR. | BRISTOL MYERS SQUIBB CO (US) | 1994-09-23 | — | — | EP | claimed |
| US-5279617-A | Using melanin precursor; oxidizing dopa compound with a ferricyanide salt | CLAIROL INCORPORATED (US) | 1994-01-18 | — | — | US | claimed |
| CN-1074113-A | Hair dyeing method and complete set of hair-dyestuff | BRISTOL MILS SQIB CO LTD (US) | 1993-07-14 | — | — | CN | claimed |
| WO-1993005759-A1 | PROCESS AND KIT FOR DYEING HAIR | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-04-01 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210220523-A1 | NO RELEASING COATED PROSTHETIC VASCULAR GRAFTS | NOS2, NOS1, NOS3 | ALOX15 747/4885KDM4E 1969/4885HIF1A 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.